02901nam 2200577Ia 450 991067806590332120200520144314.01-282-68479-597866126847910-470-57054-70-470-57053-9(CKB)2550000000003150(EBL)477737(OCoLC)609853619(SSID)ssj0000354166(PQKBManifestationID)11270501(PQKBTitleCode)TC0000354166(PQKBWorkID)10313833(PQKB)10815333(MiAaPQ)EBC477737(PPN)198273924(EXLCZ)99255000000000315020090623d2010 uy 0engur|n|---|||||txtccrEnzybiotics antibiotic enzymes as drugs and therapeutics /edited by Tomas G. Villa, Patricia Veiga CrespoHoboken, NJ John Wiley & Sonsc20101 online resource (296 p.)Includes index.0-470-37655-4 ENZYBIOTICS; CONTENTS; PREFACE; CONTRIBUTORS; 1 ENZYBIOTICS AND THEIR POTENTIAL APPLICATIONS IN MEDICINE; 2 ADVANTAGES AND DISADVANTAGES IN THE USE OF ANTIBIOTICS OR PHAGES AS THERAPEUTIC AGENTS; 3 ENZYBIOTICS AS SELECTIVE KILLERS OF TARGET BACTERIA; 4 PHYLOGENY OF ENZYBIOTICS; 5 BACTERIOPHAGE LYSINS: THE ULTIMATE ENZYBIOTIC; 6 BACTERIOPHAGE HOLINS AND THEIR MEMBRANE-DISRUPTING ACTIVITY; 7 ANTI-STAPHYLOCOCCAL LYTIC ENZYMES; 8 MEMBRANE-TARGETED ENZYBIOTICS; 9 DESIGN OF PHAGE COCKTAILS FOR THERAPY FROM A HOST RANGE POINT OF VIEW; 10 IDENTIFYING PHAGE LYTIC ENZYMES: PAST, PRESENT, AND FUTURE11 USE OF GENETICALLY MODIFIED PHAGES TO DELIVER SUICIDAL GENES TO TARGET BACTERIACONCLUDING REMARKS: THE FUTURE OF ENZYBIOTICS; INDEX Presents the latest research and applications for a new, promising approach to fighting infectious diseases Enzybiotics is a promising way of fighting bacterial or fungal infectious diseases by using viruses or viral-derived lysins. Drawing from the fields of medicinal chemistry, microbiology, genetics, and biochemistry, this book presents the state of the science in enzybiotics research, fully exploring its emerging therapeutic applications. The book begins with four chapters that review the potential applications, possible advantages, and phylogeny of enzybiotics. Next, the book eEnzymesTherapeutic useAntibacterial agentsEnzymesTherapeutic use.Antibacterial agents.615.329615.35Gonzalez Villa Tomas1342999Veiga-Crespo Patricia1343000MiAaPQMiAaPQMiAaPQBOOK9910678065903321Enzybiotics3066932UNINA