05096nam 2201381z- 450 991067437000332120231214132952.0(CKB)5680000000037538(oapen)https://directory.doabooks.org/handle/20.500.12854/81000(EXLCZ)99568000000003753820202205d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierCancer Biomarker Research and Personalized MedicineBaselMDPI - Multidisciplinary Digital Publishing Institute20221 electronic resource (428 p.)3-0365-3918-2 3-0365-3917-4 Biomarkers are measures of a biological state. The treatment of individual patients based on particular factors, such as biomarkers, distinguishes standard, generalized treatment plans from personalized medicine. Even though personalized medicine is applicable to most branches of medicine, the field of oncology is perhaps where it is most easily employed. Cancer is a heterogeneous disease; although patients may be diagnosed histologically with the same cancer type, their tumors can comprise varying tumor microenvironments and molecular characteristics that can impact treatment response and prognosis. There has been a major drive over the past decade to try and realize personalized cancer medicine through the discovery and use of disease-specific biomarkers. This book, entitled “Cancer Biomarker Research and Personalized Medicine”, encompasses 22 publications from colleagues working on a diverse range of cancers, including prostate, breast, ovarian, head and neck, liver, gastric, bladder, colorectal, and kidney. The biomarkers assessed in these studies include genes, intracellular or secreted proteins, exosomes, DNA, RNA, miRNA, circulating tumor cells, circulating immune cells, in addition to radiomic features.MedicinebicsscOncologybicsscclear cell renal cell carcinomaradiomicsWHO/ISUP nuclear grademultiphasic multidetector computed tomographytriple-negative breast cancertaxanechemotherapyGBP5Akt/mTORautophagyIL13Rα2renal cell carcinomaJAK2FOXO3telmisartanovarian cancerbioinformaticsCREB1drug perturbationlincRNA-p21rectal cancerchemoradiotherapycolorectal cancerlong non-coding RNAp53predictive biomarkerintestinal anastomosisanastomotic leakbiomarkersprecision medicinepersonalized medicinebiomarkerAmpliSeqDNA methylationepigeneticshead and neck cancersalivaliquid biopsymeta-analysisgastric cancermiddle-up-downhaptoglobinglycopeptidemass spectrometrycirculating tumor cellsprostate cancercancer vaccineimmune responsebreast cancerpredictive toolsprognostic toolstranslational researchIL6STgp130cytokine signallingtissue-based biomarkersliquid-based biomarkersradiotherapyradiosensitivity biomarkerssecretomeradioresistancebladder tumorlymphocyte-to-monocyte ratioperipheral blood parameterstumor recurrencetransurethral resectionlipidomics1H-NMRLC-MS/MSlipoprotein subfractionslipoprotein lipasecancer biomarkershepatocellular carcinomap16 expressionhead and neck squamous cell carcinomaHPV genotypingexosomeschemoresistancecomparative oncologyOne HealthmicroRNAlymph node metastasishormone-dependent carcinogenesislocalized prostate cancerprognostic factorsHNSCCMedicineOncologyMeehan Jamesedt1338657Meehan JamesothBOOK9910674370003321Cancer Biomarker Research and Personalized Medicine3058897UNINA