03178nam 2200373 450 991067405450332120230624122531.0(CKB)5400000000043624(NjHacI)995400000000043624(EXLCZ)99540000000004362420230624d2022 uy 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierThe Effects of Mycotoxins on Human and Animal Health a Special Focus on the Cellular and Molecular Mechanisms Responsible for Mycotoxin Toxicity /Daniela Eliza Marin, Ionelia TaranuBasel, Switzerland :MDPI - Multidisciplinary Digital Publishing Institute,2022.1 online resource (154 pages)3-0365-3028-2 This Special Issue gathers original studies (eight articles and one review) that aim to improve our knowledge concerning mycotoxin toxicity. The most recent research concerning the impact of zearalenone (ZEA) and the immune response is presented in a review that aims to explore the immunotoxicity produced by ZEA on different types of immune cells (phagocytes related to innate immunity and lymphocytes related to acquired immunity) as well as on immune organs, and also to identify the mechanism of action used by ZEA to modulate the immune response. The role of zearalenone in macrophage-mediated innate immunity after bacterial lipopolysaccharide (LPS) stimulation was the subject of another study, suggesting that the intake of ZEA-contaminated food might result in decreasing innate immunity. Another important study related to the co-exposure to mycotoxins and other food/feed contaminants showed that combining patulin with cadmium induces enhanced hepatotoxicity and nephrotoxicity both in vitro and in vivo, while the exposure to both deoxynivalenol and porcine circovirus has an additive effect on inflammatory cytokines by inducing the mRNA expression of interleukine-1 beta (IL-1β) and interleukine-6 (IL-6). The use of feed compounds rich in bioactive constituents for mitigating the mycotoxins effects in swine was the subject of other three studies herein, which have shown the efficacy of antioxidants from dietary grapeseed and sea buckthorn meal waste to decrease the toxicity of a diet contaminated with aflatoxin B1 or both aflatoxin B1 and ochratoxin A at the level of organs involved in the metabolism and excretion (liver and kidney), as well as at the level of secondary lymphoid organs (mesenteric lymph nodes). The use of different models (cell co-culture model, rat model) are recommended by another two studies in order to evaluate the ochratoxin A toxicity or for better prediction of the mycotoxins risk for human cancer.MycotoxinsAnimal HealthMycotoxins.Animal Health.615.95295 Marin Daniela Eliza1368102Marin Ionelia TaranuNjHacINjHaclBOOK9910674054503321The Effects of Mycotoxins on Human and Animal Health3392612UNINA02509nam 2200697Ia 450 991097033840332120200520144314.0978143843083614384308339781441640543144164054110.1515/9781438430836(CKB)2670000000016770(OCoLC)593295694(CaPaEBR)ebrary10574087(SSID)ssj0000341073(PQKBManifestationID)11947697(PQKBTitleCode)TC0000341073(PQKBWorkID)10390536(PQKB)11300509(MiAaPQ)EBC3407225(MdBmJHUP)muse14023(Au-PeEL)EBL3407225(CaPaEBR)ebr10574087(OCoLC)923403329(DE-B1597)684173(DE-B1597)9781438430836(Perlego)2674627(EXLCZ)99267000000001677020090701d2010 ub dengurcn|||||||||txtccrThe old guard /Mieczysaw Lurczynski ; translated from the Polish by Alicia Nitecki ; edited and adapted by Gerald W. Speca1st ed.Albany, N.Y. Excelsior Editions/State University of New York Pressc20101 online resource (120 p.) Excelsior EditionsOriginally published in 1946 as Stara gwardia, re-issued in 1971 in slightly abridged form under the title Alte Garde in author's Trzy sztuki (Three plays).9781438430812 1438430817 Includes bibliographical references and index.Intro -- Th e Old Guard -- Introduction -- Preface -- Cast of Characters -- The Setting -- Act I -- Act II -- Act III -- Concentration Camp Terms.A brutal and unflinchingly honest portrayal of the effects of concentration camp life on the human psyche.Holocaust, Jewish (1939-1945)DramaWorld War, 1939-1945Concentration campsDramaHolocaust, Jewish (1939-1945)World War, 1939-1945Concentration camps891.8/527Lurczynski Mieczysaw1810735Nitecki Alicia1942-1810736Speca Gerald W1810737MiAaPQMiAaPQMiAaPQBOOK9910970338403321The old guard4362208UNINA