03539nam 2201009z- 450 991066980410332120220111(CKB)5400000000041957(oapen)https://directory.doabooks.org/handle/20.500.12854/77045(oapen)doab77045(EXLCZ)99540000000004195720202201d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierNucleic Acids Conjugates for Biotechnological ApplicationsBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 online resource (130 p.)3-0365-1514-3 3-0365-1513-5 Life in biological systems is maintained by the cooperative actions of various biomolecules. With the development of chemical and biological technologies related to nucleic acids, the details of the mechanisms of such cooperative actions between nucleic acids and other biomolecules have been elucidated and further applied in various applications. In the papers published in this Special Issue, advanced research works involved in nucleic acid conjugates are reported in wide application fields, such as artificial gene regulation, biomolecular sensing, and therapeutics from leading scientists in nucleic acids chemistry and engineering.Technology: general issuesbicsscabasic siteanticancer drugaptamerartificial viral capsidBRET-based biosensorcamptothecin derivativecatalytic RNAcellular uptakeconjugatecrosslinkcytosine methyltransferasecytotoxicityDNADNA aptamerDNA-protein conjugatedrug deliverydrug delivery systemencapsulationfluorescent probefluorescent sensorsgroup I ribozymeinvasionirinotecanmacrophagesmicroRNAmRNAmultiple sclerosisn/ananocapsulenanoparticlesNLSnucleic acid binding proteinoligonucleotidepeptide-DNA conjugatePNApoly(A) tailPUFreplication initiation proteinrepulsive guidance molecule aribonucleopeptide (RNP)RNA binding proteinRNA nanostructureRNA nanotechnologyRNA regulationRNA-peptide conjugateRNA-protein complexSchiff baseself-assemblysmall interfering RNAtherapeutic nucleic acidtrans-splicingβ-annulus peptideTechnology: general issuesEndoh Tamakiedt1334190Rozners EriksedtOhtsuki TakashiedtEndoh TamakiothRozners EriksothOhtsuki TakashiothBOOK9910669804103321Nucleic Acids Conjugates for Biotechnological Applications3044801UNINA