02573nam 2200589Ia 450 991064360310332120230213211350.01-282-30110-197866123011000-470-12296-X0-470-12375-3(CKB)1000000000376001(EBL)469685(OCoLC)609848240(SSID)ssj0000353767(PQKBManifestationID)11258800(PQKBTitleCode)TC0000353767(PQKBWorkID)10302039(PQKB)10021193(MiAaPQ)EBC469685(EXLCZ)99100000000037600119850725d1980 uy 0engur|n|---|||||txtccrAdvances in enzymology and related areas of molecular biologyVolume 51[electronic resource] /edited by Alton Meister11th ed.New York Wiley19801 online resource (328 p.)Advances in enzymology and related areas of molecular biology ;51Description based upon print version of record.0-471-05653-7 Includes bibliographical references and index.ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY; CONTENTS; Cryoenzymology in Aqueous Media; The Utilization of Binding Energy in Coupled Vectorial Processes; The Reactions and the Structures of Molybdenum Centers in Enzymes; Adenosine Deaminase Deficiency and Severe Combined Immunodeficiency Disease; The Enzymology of 2,3-Bisphosphoglycerate; Author Index; Subject Index; Cumulative Indexes, Vols. 1-50Cryoenzymology in Aqueous Media (P. Douzou). The Utilization of Binding Energy in Coupled Vectorial Processes (W. Jencks). The Reactions and the Structures of Molybdenum Centers in Enzymes (R. Bray). Adenosine Deaminase Deficiency and Severe Combined Immunodeficiency Disease (L. Thompson and J. Seegmiller). The Enzymology of 2,3-Bisphosphoglycerate (Z. Rose). Subject & Author Indexes. Cumulative Indexes, Volumes 1-50.Advances in enzymologyClinical enzymologyEnzymesClinical enzymology.Enzymes.574.192612.015Meister Alton65304MiAaPQMiAaPQMiAaPQBOOK9910643603103321Advances in enzymology and related areas of molecular biology3005328UNINA04632nam 22006855 450 991080557860332120251008135056.09783031411595303141159510.1007/978-3-031-41159-5(MiAaPQ)EBC31073905(Au-PeEL)EBL31073905(DE-He213)978-3-031-41159-5(CKB)29977934600041(EXLCZ)992997793460004120240118d2023 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierGenes, Environments and Interactions Evolutionary and Quantitative Genetics Brought Up-to-date /by José M Álvarez-Castro1st ed. 2023.Cham :Springer International Publishing :Imprint: Springer,2023.1 online resource (236 pages)Print version: Álvarez-Castro, José M. Genes, Environments and Interactions Cham : Springer International Publishing AG,c2024 9783031411588 Includes bibliographical references and index.Chapter 1: Discovering The Genotype -- Chapter 2: The Primeval Theory Of Ge-Netic Effects -- Chapter 3: Genetic Effects Over One Century -- Chapter 4: Hgenetic Architectures At The Individual Level -- Chapter 5: Genetic Effects In Popula-Tions Under Linkage Equilibrium -- Chapter 6: A General Theory Of Genetic Effects -- Chapter 7: Variance Decomposition, Gene Mapping And Average Excesses—Orthogonality In The Spotlight -- Chapter 8: Applied Cases Of Advanced Genetic Modelling -- Chapter 9: The Comes And Goes Of The Black Box Perspective In Quantitative Genetics -- Chapter 10: Addendum: An Acid Test For Noia.Genetic effects are the core concepts from which quantitative genetics and the evolutionary synthesis emerged. The groundbreaking theory of genetic effects was first proposed over a century ago. This book revises that theory, both conceptually and mathematically, and brings it up-to-date. The theory here compiled is supplemented with non-previously-published developments covering the broadest spectrum of simultaneously multiallelic and multilocus architectures with autosomal and sex-linked loci Arbitrary interactions (dominance, gene-gene, gene-environment, gene-sex, and parent-of-origin interactions) are accounted for Both effects of allele substitutions from the reference of individual genotypes and in the context of populations are worked out Populations are considered regardless of any departures from equilibrium frequencies (including both departures from Hardy-Weinberg, departures from linkage equilibrium, and non-random associations between/among genes and environments) All developments are derived under the same mathematical framework, so that transformations of genetic effects between different contexts are easily allowed In brief, this book enables novel applications to current empirical paradigms (like gene-mapping and genomic prediction) while adhering to the classical conceptualization of genetic effects and variance decomposition that let quantitative genetics and the evolutionary synthesis flourish. All relevant concepts are carefully clarified and discussed from a historical perspective. The theoretical developments presented in the book are illustrated by built-in cases and applications with real data. Reassuringly, the adequacy of the theory here presented is corroborated based on the fundamentals of model development.Evolutionary geneticsBiomathematicsEvolution (Biology)Ecological geneticsPopulation geneticsEvolutionary GeneticsMathematical and Computational BiologyEvolutionary BiologyEcological GeneticsPopulation GeneticsEvolutionary TheoryEvolutionary genetics.Biomathematics.Evolution (Biology)Ecological genetics.Population genetics.Evolutionary Genetics.Mathematical and Computational Biology.Evolutionary Biology.Ecological Genetics.Population Genetics.Evolutionary Theory.576.58Álvarez-Castro Jose M.1589050MiAaPQMiAaPQMiAaPQBOOK9910805578603321Genes, Environments and Interactions3883279UNINA