03453nam 2201045z- 450 991063999110332120231214132834.03-0365-5820-9(CKB)5470000001633443(oapen)https://directory.doabooks.org/handle/20.500.12854/95832(EXLCZ)99547000000163344320202301d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierAntimicrobial Peptides Aka Host Defense Peptides – From Basic Research to TherapyBaselMDPI - Multidisciplinary Digital Publishing Institute20221 electronic resource (226 p.)3-0365-5819-5 This Special Issue reprint will address the most current and innovative developments in the field of HDP research across a range of topics, such as structure and function analysis, modes of action, anti-microbial effects, cell and animal model systems, the discovery of novel host-defense peptides, and drug development.Research & information: generalbicsscChemistrybicsscECPAMPsinfectionmurine modelGram-negative bacteriaLPShost defense peptidesmonocytesneutrophilsneutrophil–monocyte interactionextracellular trapshost defense peptideinnate immunityNF-κBpoly I:Ctoll-like receptor 3mucus of Cornu aspersumpeptide fraction MW < 10 kDaEscherichia coli NBIMCC 8785SEMfluorescence and digital assaysantibacterial effectoral cavityhuman cathelicidinantimicrobial peptidesimmunomodulationoncolytic peptidescancermembrane integritybulky non-nature amino acidDAMPsdrug designantimicrobial peptidomimetichydrogel-based systemhyaluronic acidanti-infective activityskin infectionsantimicrobial peptideexpressioninteinself-cleavagececropin-likeapolipoprotein Ehost defenseaggregationbody fluidAMPinteraction networkchemical barriercationic antimicrobial peptideslength dependent activityantimicrobial activityhemolysisvesicle leakagesolid-state 31P-, 15N- and 19F-NMRβ-stranded peptidesβ-sheetsstructure and orientation of peptides in membranesResearch & information: generalChemistryPetrlova Jitkaedt1290749Petrlova JitkaothBOOK9910639991103321Antimicrobial Peptides Aka Host Defense Peptides – From Basic Research to Therapy3021581UNINA