05790nam 2201885z- 450 991063999000332120231214133618.03-0365-5927-2(CKB)5470000001633454(oapen)https://directory.doabooks.org/handle/20.500.12854/95801(EXLCZ)99547000000163345420202301d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierStrategies to Improve Antineoplastic Activity of Drugs in Cancer ProgressionBaselMDPI - Multidisciplinary Digital Publishing Institute20221 electronic resource (416 p.)3-0365-5928-0 The aim of this Special Issue is to collect reports regarding all the recent strategies, directed at the improvement of antineoplastic activity of drugs in cancer progression, engaging all the expertise needed for the development of new anticancer drugs: medicinal chemistry, pharmacology, molecular biology, and computational and drug delivery studies.Research & information: generalbicsscBiology, life sciencesbicsscEGR-1flavonoid(E)-5-((4-oxo-4H-chromen-3-yl)methyleneamino)-1-phenyl-1H-pyrazole-4-carbonitrileMDA-MB-231MMP9TNFαpancreatic ductal adenocarcinomacyclodextrin inclusion complexphase solubility studiespreformulation studiesbiphenylnicotinamide derivativesdual inhibitorEGFRVEGFR2ligand-based pharmacophoremolecular dockingmolecular dynamicsleukemiasdoxorubicininflammationdrug deliverytumor targetingelastin-like polypeptidecell penetrating peptidematrix metalloproteinasedoxorubicin resistancephotosensitizer delivery systemPAMAM dendrimerphotodynamic therapycytotoxicityphototoxicitycolorectal adenocarcinomadicarboximideschemical synthesisapoptosiskinasesanticancergene profilingSARbiomarkerscolorectal cancerearly detection examinationliquid biopsypersonalized medicinetumor treatmentexosomesctDNACTCcytotoxic activitypyrazole derivativesMTT assayADMET analysissingle-crystal diffractionFTIR spectroscopyNMR spectroscopy thermogravimetric analysisacute myelogenous leukemiaplateletsmicroparticlesγδ T cellsimmunotherapytumor resistancecombination therapytumor microenvironmentimmune checkpoint inhibitorneuroblastomamolecular iodinecyclophosphamidexenograftsmetronomic therapytamoxifenCYP2D6MCF-7Ishikawa cellsSERMTNBCuterotrophicα-mangostinpoly(amidoamine) dendrimertargeted drug deliverybiotin targetingglioblastoma multiformesquamous cell carcinomaantiparasitic therapydiclofenacindomethacinoleanolic acid derivative conjugatesNF-κBNrf2MAPKsPSN-1 cellsreactive oxygen speciesglioblastomabrain tumorextracellular vesiclespancreatic cancerpaclitaxelclathrinendocytosissulforaphanenicotinemetalloproteinase-9gastric cancercell invasionArylquin 1colon cancertumor progressionazelastineoxidative stressautophagymitotic catastrophechronic myeloid leukemiaimatinibtyrosine kinaseketoconazoleP-glycoproteindrug efflux transporternon-small-cell lung cancercisplatin resistancealdehyde dehydrogenaseisothiocyanatesdisulfiramepithelial to mesenchymal transitionaminopeptidase NacetamidophenonesSchiff basessemicarbazonesthiosemicarbazonesinhibition of proliferationResearch & information: generalBiology, life sciencesStefanachi Angelaedt1323363Stefanachi AngelaothBOOK9910639990003321Strategies to Improve Antineoplastic Activity of Drugs in Cancer Progression3035463UNINA