03728nam 2200625 450 991063987810332120240228160751.09783031129742(electronic bk.)978303112973510.1007/978-3-031-12974-2(MiAaPQ)EBC7167832(Au-PeEL)EBL7167832(CKB)25936425400041(DE-He213)978-3-031-12974-2(OCoLC)1369656710(BIP)084962175(PPN)267807406(EXLCZ)992593642540004120230506d2023 uy 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierCancer stem cell markers and related network pathways /edited by Shihori Tanabe1st ed. 2022.Cham, Switzerland :Springer,[2023]©20231 online resource (163 pages)Advances in Experimental Medicine and Biology,2214-8019 ;1393Print version: Tanabe, Shihori Cancer Stem Cell Markers and Related Network Pathways Cham : Springer International Publishing AG,c2023 9783031129735 1. Epithelial-mesenchymal transition and cancer stem cells -- 2. The transcription factors Zeb1 and Snail induce cell malignancy and can-cer stem cell phenotype in prostate cells, increasing androgen synthesis ca-pacity and therapy resistance -- 3. ERBB signaling pathway in cancer stem cells -- 4. Functional and molecular characters of cancer stem cells through devel-opment to establishment -- 5. Microenvironment in cancer stem cells -- 6. Cancer stem cells contribute to drug resistance in multiple different ways -- 7. Abnormal glycosylation in cancer cells and cancer stem cells as a thera-peutic target.This book entitled “Cancer Stem Cell Markers and Related Network Path-ways” is about cancer stem cell (CSC) markers and the molecular network pathways. CSCs play an important role in the cancer drug resistance, metastasis and recurrence. Epithelial-mesenchymal transition (EMT) is closely related to CSC phenotype. This book covers various aspects of the molecular networks related to CSCs including the important phenotypic change such as EMT. Readers will discover the importance of the identification of CSC markers and EMT-related molecules in CSC network pathways. The CSC signaling pathways and EMT molecular network pathways attract researchers in the field to define the cancer therapeutic targets. Cancer environment is important in the acquisition of CSC phenotype in cells. The revealing of this CSC mystery is across 7 chapters. The topic of this book is particularly relevant to research in the field of cancer and stem cells, as well as the network pathways. We hope that this book helps the readers to be interested in understanding why the CSC concept is important and attractive.Advances in Experimental Medicine and Biology,2214-8019 ;1393Biochemical markersStem cellsCèl·lules marethubMarcadors bioquímicsthubCitodiagnòsticthubLlibres electrònicsthubInternal MedicineMedicalBiochemical markers.Stem cells.Cèl·lules mareMarcadors bioquímicsCitodiagnòstic610.28Tanabe ShihoriedtMiAaPQMiAaPQMiAaPQ9910639878103321Cancer Stem Cell Markers and Related Network Pathways3003347UNINA