03408nam 2200841z- 450 991063778210332120231214133138.03-0365-5760-1(CKB)5470000001631716(oapen)https://directory.doabooks.org/handle/20.500.12854/94532(EXLCZ)99547000000163171620202212d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierExtraction and Fractionation Processes of Functional Components in Food EngineeringBaselMDPI - Multidisciplinary Digital Publishing Institute20221 electronic resource (122 p.)3-0365-5759-8 This Special Issue on the "Extraction and Fractionation Processes of Functional Components in Food Engineering" aims to bring together novel advances in the development and application of innovative processing strategies to extract, isolate, and modify food compounds to produce ingredients and foods with improved nutritional, functional, and biological properties. Topics include: - Development of innovative processing strategies to extract, modify, and recover food compounds. - Effects of industrial processes on the functionality and biological activities of food compounds. - Bioconversion of agricultural waste streams and food byproducts into added valuable compounds. - Challenges associated with processing scale-up.Technology: general issuesbicsscHistory of engineering & technologybicsscterpenepineneEscherichia coliwheywhey permeatebiosynthesismicrobialpeptideshydrolysateshypertensionaqueous extraction processextraction yieldscream demulsificationoil recoveryalmond flourwalnut oilrancidityinduction timerancimatresponse surface methodologyacid-soluble collagensnakehead fishfish skinthe mixture of skin and scaledenaturation temperatureFTIRfood proteinsnovel extraction methodologiesenzymatic hydrolysisbioactive peptidesseedssupercritical CO2 extractionsolvent extractionexpeller pressingenzyme-assisted aqueous extractiontechno-economic analysislife cycle assessmentTechnology: general issuesHistory of engineering & technologyDe Moura Bell Juliana Maria Leite Nobregaedt1296431Hernández-Ledesma BlancaedtSilva Roberta Claro daedtDe Moura Bell Juliana Maria Leite NobregaothHernández-Ledesma BlancaothSilva Roberta Claro daothBOOK9910637782103321Extraction and Fractionation Processes of Functional Components in Food Engineering3024066UNINA05204nam 22006975 450 991035029430332120200702092354.0981-13-8094-510.1007/978-981-13-8094-5(CKB)4100000008876865(DE-He213)978-981-13-8094-5(MiAaPQ)EBC5776072(PPN)236523279(EXLCZ)99410000000887686520190513d2019 u| 0engurnn|008mamaatxtrdacontentcrdamediacrrdacarrierOne-Step Generation of a Drug-Releasing Microarray for High-Throughput Small-Volume Bioassays /by Seo Woo Song1st ed. 2019.Singapore :Springer Singapore :Imprint: Springer,2019.1 online resource (XXI, 52 p. 46 illus., 40 illus. in color.) Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053981-13-8093-7 Abstract -- Table of Contents -- List of Tables -- List of Figures -- Chapter 1. Introduction -- 1.1. High-Throughput Small-Volume Bioassays -- 1.2. Developmental Goal for the ‘Pipetting-Free’ HTS Platforms -- 1.3. Main Concept: One-Step Generation of a Drug-Releasing Microarray-on-a-Chip by Self-Assembly of Drug-Laden Microparticles (DLPs) -- Chapter 2. System Development -- 2.1. Sealing-Film Assisted Seeding Method for Saving Cell Consumptions -- 2.2. Chip and Jig Development -- 2.3. Preparation of DLPs Library -- 2.4. Decoding Microparticles -- 2.5. Statistical Analysis for Duplications -- Chapter 3. Application: Screening of Sequential Drug Combinations -- 3.1. Therapeutic Benefit of Sequential Drug Combination Based on Rewiring of Intracellular Pathways -- 3.2. Screening of Sequential Drug Combination Using a Partipetting Platform -- 3.3. Proof-of-Concept: Sequential Combinatorial Cell Staining Assay by Replacement of the Drug Chip -- 3.4. Screening of Sequential Combinatorial Drugs with EGFR Inhibitor Followed by Genotoxin against Triple Negative Breast Cancer (TNBC) -- Chapter 4. Conclusion and Discussion -- Bibliography.This thesis demonstrates a technology that enables pipetting-free high-throughput screening (HTS) on a miniaturized platform, eliminating the need for thousands of one-by-one pipetting and conventional liquid handling systems. This platform enhances accessibility to HTS and enables HTS to be used in small-to-medium scale laboratories. In addition, it allows large-scale combinatorial screening with a small number of valuable cells, such as patients’ primary cancer cells. This technique will have a high impact for widespread use of HTS in the era of personalized medicine. In this thesis, the author firstly describes the need and concept of ‘partipetting’ for pipetting-free HTS platform. It is realized by the one-step pipetting and self-assembly of encoded drug-laden microparticles (DLPs) on the microwells. Next, the technical implementations required for the platform demonstration are described. It includes preparation of encoded DLPs, plastic chip fabrication, and realization of automated system. Lastly, screening of sequential drug combinations using this platform is demonstrated. This shows the potential of the proposed technology for various applications.Springer Theses, Recognizing Outstanding Ph.D. Research,2190-5053Biomedical engineeringMicroarraysAmorphous substancesComplex fluidsNanotechnologyMicrobiologyBiotechnologyBiomedical Engineering and Bioengineeringhttps://scigraph.springernature.com/ontologies/product-market-codes/T2700XMicroarrayshttps://scigraph.springernature.com/ontologies/product-market-codes/B12050Soft and Granular Matter, Complex Fluids and Microfluidicshttps://scigraph.springernature.com/ontologies/product-market-codes/P25021Nanotechnology and Microengineeringhttps://scigraph.springernature.com/ontologies/product-market-codes/T18000Applied Microbiologyhttps://scigraph.springernature.com/ontologies/product-market-codes/C12010Microengineeringhttps://scigraph.springernature.com/ontologies/product-market-codes/C12040Biomedical engineering.Microarrays.Amorphous substances.Complex fluids.Nanotechnology.Microbiology.Biotechnology.Biomedical Engineering and Bioengineering.Microarrays.Soft and Granular Matter, Complex Fluids and Microfluidics.Nanotechnology and Microengineering.Applied Microbiology.Microengineering.610.28Song Seo Wooauthttp://id.loc.gov/vocabulary/relators/aut929406BOOK9910350294303321One-Step Generation of a Drug-Releasing Microarray for High-Throughput Small-Volume Bioassays2088884UNINA