05255nam 2201465z- 450 9910619470903321202210253-0365-5357-6(CKB)5670000000391565(oapen)https://directory.doabooks.org/handle/20.500.12854/93226(oapen)doab93226(EXLCZ)99567000000039156520202210d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierPig Genomics and GeneticsMDPI - Multidisciplinary Digital Publishing Institute20221 online resource (318 p.)3-0365-5358-4 In this Special Issue, we present the state of the art in the field of pig genetics and genomics, including the identification of gene candidates linked to important pig traits and to nutritional modifications, with the aim of collecting the most recent advances. The published manuscripts focused on high-throughput methodologies, such as RNA sequencing, ATAC-seq, MACE-seq, chip-seq, and RRBS, and covered other fields of pig genetics. The pig (Sus scrofa) is the most common large mammal in the world. The Sus genus includes domestic pig and wild boar. Since the draft reference genome sequence of S. scrofa was assembled in 2012, the processes of identification of genes related to important phenotypic traits and of search of genetic markers for pig selection have been significantly refined. In addition, the newest wide-range high-throughput techniques, including microarrays, next-generation sequencing, and the recent PacBio sequencing platform providing ultra-long sequencing reads, allow identifying gene mutations and gene candidates throughout the whole genome, transcriptome, or epigenome and estimating quantitative traits important for breeding as well as the genetic backgrounds of inherited diseases.Biology, life sciencesbicsscResearch and information: generalbicsscZoology and animal sciencesbicssc3'quant mRNA-seqadipogenesisalternative splicingantimicrobial peptideantiviral responseAQP3circRNAscoagulation system dysregulationcongenital defectsCRISPR/Cas9CRISPR/Cas9 systemdisease modelsdisease-resistant animalsDNA methylationDNMT3BdomainDurocDuroc pigsendometriumextracellular matrixfat depositionfatnessfatty acidsgene expressiongenetic engineeringgenetically modified pigsgenome modificationsglobal gene expressiongrowth traitsGWAS (Genome-Wide Association Studies)heat stressHezuo Tibetan pigHMOX1 genehypothalamusIFN-βintramuscular fatisoformlipid metabolismlitter sizelncRNAlymphatic systemmeat qualitymetabolic diseasesmetabolomemicroarrayn/aNGSNMRnon-homologous DNA ends joining (NHEJ)nutrigenomicsobesityoff-targetpigpigspoly (I:C)porcine alveolar macrophagesporcine β-defensin 2precision medicineproliferationpromoterproteinPRRSVpubertal genespubertyrecombinant proteinsRNA-seqRNA-Seqseminal plasmasingle nucleotide polymorphismskeletal muscle fiberSNPSNP (single nucleotide polymorphism)SNP array genotypingSus scrofaswineTIDE analysisTNF-αtotal number born alivetranscripttranscriptional regulationtranscriptomicstransgenic pigsTRIM26VSVweighted single-step GWASwhole-genome sequencingxenoantigenxenotransplantationBiology, life sciencesResearch and information: generalZoology and animal sciencesPiórkowska Katarzynaedt1291908Ropka-Molik KatarzynaedtPiórkowska KatarzynaothRopka-Molik KatarzynaothBOOK9910619470903321Pig Genomics and Genetics3022066UNINA