00972nam0-2200337li-450 99000014014020331620180312154736.00-7273-0115-20014014USA010014014(ALEPH)000014014USA01001401420001109d1991----km-y0itay0103----baengGBAutomotive engineering plasticsRichard WoodLondonPentech Press1991autoveicoli tecniche di fabbricazione629.234.Wood,Richard144306Sistema bibliotecario di Ateneo dell' Università di SalernoRICA990000140140203316629.234 WOO0002750BKTEC1995080720001110USA01171220020403USA011621PATRY9020040406USA011610Automotive engineering plastics1491628UNISA03857nam 2200913z- 450 9910619468703321202210253-0365-4600-6(CKB)5670000000391587(oapen)https://directory.doabooks.org/handle/20.500.12854/93174(oapen)doab93174(EXLCZ)99567000000039158720202210d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierNanoparticle-Macrophage InteractionsImplications for Nanosafety and NanomedicineMDPI - Multidisciplinary Digital Publishing Institute20221 online resource (208 p.)3-0365-4599-9 Nanoparticles (NPs) offer unique properties for biomedical applications, leading to new nanomedicines. Recent examples of advanced nanoparticle-based nanomedicines are COVID-19 RNA vaccines. Regardless of the delivery route of the NPs into the body (intravenous or subcutaneous injection, oral, intranasal, etc.), NPs inevitably come into contact with immune cells, such as macrophages. Macrophages are phagocytizing cells that determine the fate and the lifetime of NPs in relevant biological fluids or tissues, which has consequences for both nanosafety and nanomedicine. The aim of this Special Issue is to cover recent advancements in our understanding of NP-macrophage interactions, with a focus on in vitro models for nanosafety and novel nanomedicine approaches that allow the modulation of the immunological profile of macrophages. The current Special Issue compiles nine papers: seven research articles and two review articles. The original articles include studies on the interaction of different nanomaterials, such as multi-walled carbon nanotubes (MWCNTs), amorphous silica, gold nanoparticles, lipid carriers, and microspheres, with macrophages in different scenarios.Nanoparticle-Macrophage Interactions Medicine and Nursingbicssc2D cultures3D culturesanti-inflammatorybovine serum albuminCaco-2 cellscarbon nanotubecell uptakechemokineschronic woundclass A type 1 scavenger receptorsCrohn's diseasecytotoxicitydevicedrug deliveryfoot ulcergold nanoparticlesICP-MS analysis of cell bound SiO2immune systemin vitro modelsin vitro testinginflammationinnate immunityinnate memorymacrophagemacrophage-nanoparticle interactionmacrophagesmonocytesmulti-walled carbon nanotubesn/ananomaterialnanomaterialsnanoparticlenanoparticlesnanostructured lipid carriersNR8383 alveolar macrophageoral administrationosteoarthritisphagocytosisprotein coronarifabutinscavenger receptorsynthetic amorphous silicatranscriptomicswound healingzebrafishMedicine and NursingBondarenko Olesjaedt1309484Torres Andón FernandoedtBondarenko OlesjaothTorres Andón FernandoothBOOK9910619468703321Nanoparticle-Macrophage Interactions3029367UNINA