05857nam 2201489z- 450 9910619464603321202210253-0365-4990-0(CKB)5670000000391628(oapen)https://directory.doabooks.org/handle/20.500.12854/93236(oapen)doab93236(EXLCZ)99567000000039162820202210d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierWomen in Bioorganic ChemistryMDPI - Multidisciplinary Digital Publishing Institute20221 online resource (288 p.)3-0365-4989-7 Issues relating to the gender schism and its effect on the career advancement of women in the Academy, especially in the field of STEM disciplines, deserve our attention and the efforts of all the scientific community to mitigate the gender gap. In order to embrace gender equality, recognize the career progression of women, and to celebrate the achievements of women in the field of bioorganic chemistry, we present contributions both from highly renowned female scientists and young female researchers who are in the early stages of their careers. This Special Issue includes fifteen manuscripts, including eleven high-quality research articles and four comprehensive review articles in the area of bioorganic chemistry, published from mid-2020 to early 2022. The scope of this Special Issue covers a wide range of topics at the organic chemistry-biology interface, including the synthesis and derivatization of natural compounds and their analogues, and the investigation of their biological activities in the human health field (for instance as antitumorals, antioxidants and antimicrobial agents), as well as their possible application in the crop protection field as agrochemicals. An example of nanoparticle-based biomaterial is also included. The techniques employed, besides organic synthesis, are in silico studies (docking procedures and molecular modeling), FT-IR spectroscopy, laser diffraction, PET, fluorescence, STD-NMR studies, enzymatic evaluation, experiments on cell lines and in vivo studies on mice.Industrial chemistry and chemical engineeringbicsscTechnology: general issuesbicssc(p)ppGpp1-deoxy-dxylulose 5-phosphate reductoisomerase (DXR)2-C-methyl-derythritol 4-phosphate (MEP) pathway3D molecular dockingamelogeninamelogenin-derived peptidesaminoproline scaffoldAMRanti-cancerantibioticsanticancer activityantimicrobialantimicrobialsantiproliferative activitybenzamidebetulinic acidbiochemical studiesBODIPYboronboron neutron capture therapycancercannabidiolchiralitychiropticalcytotoxicityd-annulated steroidsdental cariesdeoxyxylulose phosphate reductoisomerasedispirooxindolesenamel remineralisationenantiomersenzyme inhibitionfluorescence probefluorescentfosmidomycinfragment screeningFT-IR spectroscopyglycosidasegold nanoparticlesheterohelicenehydrazoneshydroxyapatiteiminosugarsin vivo studiesinhibition mechanisminhibitorsinsect trehalaseintegrin targetinginterrupted Nazarov cyclizationisoprenoid biosynthesisJack bean α-mannosidaselaser diffractionleucine-rich amelogenin peptidesleukocyte integrinsLewis acidligand designlipidsliposomesmammalian trehalasemolecular mechanismsmultivalencyn/anatural compoundsneurological diseasesneuroprotective effectsp53/MDM2 interactionpenetration enhancerspentacyclic steroidspeptidomimetic synthesispersistersPETphthalimidepostprandial hyperglycemiapyreneresolutionscrew-shaped compoundsselectivitySTD-NMRstratum corneumStrigolstrigolactonessustainable agriculturesynergistic effectterpenesthermal shift assaytrehalosetyrosine-rich amelogenin peptidesα-glucosidaseα,α-difluorophosphonateβ-galactosidase activityIndustrial chemistry and chemical engineeringTechnology: general issuesCardona Francescaedt1314135Parmeggiani CamillaedtMatassini CamillaedtCardona FrancescaothParmeggiani CamillaothMatassini CamillaothBOOK9910619464603321Women in Bioorganic Chemistry3031750UNINA