03422nam 2200889z- 450 9910619464403321202210253-0365-5130-1(CKB)5670000000391630(oapen)https://directory.doabooks.org/handle/20.500.12854/93232(oapen)doab93232(EXLCZ)99567000000039163020202210d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierEchinoderms Metabolites: Structure, Functions and Biomedical Perspectives IIMDPI - Multidisciplinary Digital Publishing Institute20221 online resource (192 p.)3-0365-5129-8 The book largely reflect the structural diversity of echinoderm metabolites including triterpene glycosides and fucosylated chondroitin sulfates, as well as branched fatty acids, di- and triacylglycerols and other lipid classes from the sea cucumbers, polyhydroxysteroids from starfish and different classes of sphingolipids from sea cucumbers and starfish. Finally, the MS-based metabolomic approach, which is very helpful for the estimation of such diversity, is discussed. The materials from the Special Issue also illustrate the biomedical potential of the presented metabolites as cytotoxins and anticoagulants. The in silico approach broadens the possibilities to investigate the mechanisms of the action of membranolytic compounds.Echinoderms MetabolitesChemistrybicsscResearch and information: generalbicssc   triterpene glycosides1-O-alkylglyceryl ether3D cultureanticoagulant activityAsteroideabêche-de-merbiological activityBohadschia argusceramidescerebrosideschitonoidosidescytotoxic activitydiacylglycerol etherdisulfated steroidsfucan sulfatesfucosylated chondroitinsulfatesgangliosideshemolyticHolothuria (Theelothuria) spiniferaHolothuroideakurilosideslipidsmass spectrometrymembranolytic actionmetabolomic profilingmetabolomicsmolecular dynamic simulationneuritogenic activityNMR spectranutraceutical oilspolyhydroxysteroidsPsolus chitonoidesPteraster marsippussea cucumbersialic acidsphingolipidsstarfishsteroid glycosidesThyonidium kurilensistriterpene glycosidesChemistryResearch and information: generalKalinin Vladimir Iedt1327009Silchenko Alexanra SedtKalinin Vladimir IothSilchenko Alexanra SothBOOK9910619464403321Echinoderms Metabolites: Structure, Functions and Biomedical Perspectives II3038943UNINA