05092nam 2201417z- 450 991061946390332120231214133024.03-0365-5349-5(CKB)5670000000391635(oapen)https://directory.doabooks.org/handle/20.500.12854/93257(EXLCZ)99567000000039163520202210d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierRecent Advances in Volatile Organic Compound Analysis as Diagnostic BiomarkersMDPI - Multidisciplinary Digital Publishing Institute20221 electronic resource (224 p.)3-0365-5350-9 Volatile organic compounds (VOCs) are a diverse group of carbon-based molecules that are volatile at ambient temperatures and are emitted by an organism as a result of metabolic processes of cells and associated microbiome. The qualitative and quantitative profile of VOCs in biological fluids can vary depending on the physiological changes. Therefore, the pattern of volatile metabolites may reflect the presence of several diseases. This has been intensively investigated in the last few decades, resulting in an increasing number of studies focused on new volatile biomarker discovery.This reprint aimed to summarize the recent findings related to VOCs detected in various biological fluids such as breath, urine and feces for biomedical applications. The content covers various topics, including but not limited to biomedical/medical application of VOC analysis, biomarker discovery, and novel approaches for sampling and analyzing VOCs.Research & information: generalbicsscChemistrybicsscliquid–liquid extractionvolatile compoundsurinemethod optimizationGC-MS1H-NMRiron deficiency anaemiairon supplementationvolatile organic compounds (VOCs)intestinal metabolomegut microbiomeCDHmicrobiomeVOCsspiroergometryoutcomeexhaled breatheNosesmokingasthmaCOPDNTD-GC-MSbreathlung cancerbiomarkersvolatile organic compoundsurine analysiscomprehensive two-dimensional gas chromatographykidney diseasesurinary biomarkershepatocellular carcinomadiagnosisheadspace analysisuntargeted analysisbreath analysiscancer biomarkersvolatolomicswhole grainryecomprehensive two-dimensional gas chromatography–mass spectrometrydietary fibere-noseelectronic nosebreathing rhythmmechanical ventilationanesthesiasupplemental oxygenoxygen toxicitylipid peroxidationvolatile aldehydespentanalhexanalclassification modelsdairy cowsfecal headspaceMycobacterium avium ssp. paratuberculosis (MAP)paratuberculosisrandom foreststable airvolatile organic compound (VOC)biomarkerMCC–IMSventilator-induced lung injurymetabolomefecesneonatesfermentationproteincarbohydrateshort chain fatty acidmetabolitesvolatile organic compoundacute gastritisantibiotic treatmenttreatment dynamics: microbiotamid-infrared spectroscopyshort-chain fatty acidalpha-keto acidHelicobacter pyloriMOX sensorslow sensing chamber volumecalibration transferstandard samplespiecewise direct standardizationcorrelation alignmentbreath samplingpattern recognitionResearch & information: generalChemistryDrabińska Nataliaedt1328779Lacy Costello Ben deedtDrabińska NataliaothLacy Costello Ben deothBOOK9910619463903321Recent Advances in Volatile Organic Compound Analysis as Diagnostic Biomarkers3038942UNINA