02872nam 2200841z- 450 991059507240332120231214133113.0(CKB)5680000000080802(oapen)https://directory.doabooks.org/handle/20.500.12854/92146(EXLCZ)99568000000008080220202209d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierNew Insights into the Pathogenesis and Therapies of IgA NephropathyBaselMDPI Books20221 electronic resource (194 p.)3-0365-5041-0 3-0365-5042-9 IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide and a frequent cause of kidney failure. Better understanding of the pathogenesis of IgAN and the related genetic, immunological, and cellular susceptibility factors are needed to enable the development of effective disease-specific therapy. This book brings together international experts to provide clinical and experimental studies and reviews with an emphasis on early diagnosis, prognosis, disease pathogenesis, determination of disease activity, and new strategies for treatment for IgAN.Medicinebicsscobesitymesangial matrix expansionbody mass indexIgA nephropathyIgA VasculitisIgA NephropathyadultschildrenpresentationphysiopathologygeneticsprognosistreatmentIgAclinical trialskidney mesangiummouse modelaberrantly glycosylated IgA1galactose-deficient IgA1glycosylation of IgA1biomarkercomplement C3O-glycosylationIgA1autoantibodyimmune complexcomplementkidneynephrologyIgA vasculitisnephritiskidney biopsyplasma cellsCD38renal pathologyurinary galactose-deficient IgA1KM55crescentsproteinuriaglomerular filtration rateOxford scoreMedicineSuzuki Hitoshiedt921974Novak JanedtSuzuki HitoshiothNovak JanothBOOK9910595072403321New Insights into the Pathogenesis and Therapies of IgA Nephropathy3039264UNINA