02415nam 2200757z- 450 991059506950332120230220(CKB)5680000000080836(oapen)https://directory.doabooks.org/handle/20.500.12854/92087(oapen)97459(EXLCZ)99568000000008083620202209d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierHallmarks of Parkinson's DiseaseBaselMDPI - Multidisciplinary Digital Publishing Institute20221 electronic resource (124 p.)3-0365-5015-1 3-0365-5016-X This book gathers a collection of review articles aiming to provide an update of the current knowledge on PD pathogenesis. It notably includes an overview of several key cellular dysfunctions underlying the etiology of Parkinson's disease, including ER stress, mitophagy and alpha-synuclein-linked pathology.MedicinebicsscNeurosciencesbicsscMedicine and NursingbicsscParkinson’s diseaseunfolded protein responsereticulum endoplasmicgeneticsalpha-synucleinprion-like spreadingcell-to-cell transferneurodegenerationmitochondrial dysfunctionPINK1neuronsastrocytesmicrogliaα-synucleinexocytosislipidsmembranesParkinson diseaseSNARE complexsynapsevesicle fusiontherapeutic targetprotein quality controlmitochondrial quality controlubiquitinalpha-synmitophagyParkinmito-Keimamito-QCmito-SRAIMedicineNeurosciencesMedicine and NursingAlves Da Costa Cristineedt1332308Alves Da Costa CristineothBOOK9910595069503321Hallmarks of Parkinson’s Disease3040810UNINA