02277nam 2200721z- 450 991059506950332120231214133108.0(CKB)5680000000080836(oapen)https://directory.doabooks.org/handle/20.500.12854/92087(EXLCZ)99568000000008083620202209d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierHallmarks of Parkinson’s DiseaseBaselMDPI Books20221 electronic resource (124 p.)3-0365-5015-1 3-0365-5016-X This book gathers a collection of review articles aiming to provide an update of the current knowledge on PD pathogenesis. It notably includes an overview of several key cellular dysfunctions underlying the etiology of Parkinson’s disease, including ER stress, mitophagy and alpha-synuclein-linked pathology.MedicinebicsscNeurosciencesbicsscParkinson’s diseaseunfolded protein responsereticulum endoplasmicgeneticsalpha-synucleinprion-like spreadingcell-to-cell transferneurodegenerationmitochondrial dysfunctionPINK1neuronsastrocytesmicrogliaα-synucleinexocytosislipidsmembranesParkinson diseaseSNARE complexsynapsevesicle fusiontherapeutic targetprotein quality controlmitochondrial quality controlubiquitinalpha-synmitophagyParkinmito-Keimamito-QCmito-SRAIMedicineNeurosciencesAlves Da Costa Cristineedt1332308Alves Da Costa CristineothBOOK9910595069503321Hallmarks of Parkinson’s Disease3040810UNINA