04585nam 2200589 450 991058346320332120190404152934.00-12-802165-9(CKB)3710000000581827(EBL)4387032(SSID)ssj0001674811(PQKBManifestationID)16477675(PQKBTitleCode)TC0001674811(PQKBWorkID)15017119(PQKB)10308866(MiAaPQ)EBC4387032(PPN)193845245(EXLCZ)99371000000058182720160213h20162016 uy 0engur|n|---|||||txtccrNutraceuticals efficacy, safety and toxicity /edited by Ramesh C. GuptaAmsterdam, [Netherlands] :Academic Press,2016.©20161 online resource (1042 p.)Description based upon print version of record.0-12-802147-0 Includes bibliographical references at the end of each chapters and index.Front Cover; Nutraceuticals; Copyright Page; Dedication; Contents; List of Contributors; Introduction; Introduction; References; I. Applications of Nutraceuticals in Common Diseases and Disorders; 1 Nutraceuticals in CNS Diseases: Potential Mechanisms of Neuroprotection; Introduction; Polyphenols; Counteracting Oxidative Stress as a Mechanism of Neuroprotection; Direct Antioxidant Action of Quercetin; Potential Role of Hormesis in Neuroprotection; Modulation of the Nrf2-ARE Pathway as a Mechanism of Quercetin NeuroprotectionModulation of Paraoxonase 2 (PON2) as a Potential Novel Mechanism of Quercetin NeuroprotectionParaoxonase 2; Paraoxonase 2 in the Central Nervous System; Gender Differences in Paraoxonase 2 Expression; Modulation of Paraoxonase 2; Modulation of Paraoxonase 2 by Quercetin; The Issue of Metabolites; Concluding Remarks and Future Directions; Acknowledgments; References; 2 Prevention of Neurodegenerative Disorders by Nutraceuticals; Introduction; Nutraceuticals for the Prevention and Amelioration of AD; Nutraceuticals for the Prevention and Amelioration of PDNutraceuticals for the Prevention and Amelioration of ASDConcluding Remarks and Future Directions; References; 3 Cognitive Effects of Nutraceuticals; Introduction; Biological Basis of Cognition; Overview of Cognition; Cellular Basis of Information Storage; Synaptic Plasticity as a Physical Basis for Memory; Biological Basis of Dementia; Nutraceuticals with Potential Cognitive Enhancing Functions; Ginkgo biloba; Positive Effects; Potential Mechanisms; Negative or Null Effects; Bacopa monnieri; Positive Effects; Potential Mechanisms; Negative or Null Effects; Ginseng; Positive EffectsPotential MechanismNegative or Null Effects; Phosphatidylserine; Positive Effects; Potential Mechanisms; Negative or Null Effects; Caffeine; Positive Effects; Potential Mechanisms; Negative or Null Effects; Centella asiatica, Ephedra sinica, and Crocus sativus; Potential Concerns of Cognitive Enhancement; Concluding Remarks and Future Directions; References; 4 Nutraceuticals in Cardiovascular Diseases; Introduction; Cardiac Dysfunction; Features of Cardiac Disease; Hypertension; Coronary Artery Disease (CAD)-Atherosclerosis; Ischemia; Hypertrophy; Oxidative Stress; Vascular InjuryBiomarkers of Heart DiseaseTherapeutic Response to Heart Disease; Phytotherapeutic Strategies; Nutraceuticals; Cruciferous Vegetables; Bulbous Plants; Tea; CoQ10; Turmeric; Grape Skin; Fish Oil/Olive Oil; Vegetables; Carnitine; Soy; Concluding Remarks and Future Directions; References; 5 Antiatherosclerotic Efficacy of Nutraceuticals; Introduction; Pathogenesis of Atherosclerosis and Possible Points of Therapeutic Intervention; Role of LDL; Atherosclerotic Plaque Formation; Existing and Emerging Antiatherosclerotic Therapies; Nutraceuticals with Antiatherosclerotic ActivityAntiatherogenic Natural AgentsDietary supplements industryUnited StatesPharmaceutical industryUnited StatesVitamin industryUnited StatesDietary supplements industryPharmaceutical industryVitamin industry381.456646Gupta Ramesh C(Ramesh Chandra),1949-MiAaPQMiAaPQMiAaPQBOOK9910583463203321Nutraceuticals2141214UNINA