01856nam 2200433 450 991058336160332120180505091515.00-12-812279-X0-12-812259-5(CKB)3710000001442211(MiAaPQ)EBC4921003(PPN)228026504(EXLCZ)99371000000144221120170815h20172017 uy 0engurcnu||||||||rdacontentrdamediardacarrierA paradigm shift to prevent and treat Alzheimer's disease from monotargeting pharmaceuticals to pleiotropic plant polyphenols /Howard Friel and Sally FrautschyLondon, England :Academic Press,2017.©20171 online resource (275 pages) illustrationsIncludes bibliographical references at the end of each chapters and index.Part I. Pleiotropism -- Monotargeting versus multitargeting -- The pleiotropic pharmacology of plant polyphenols -- Part II. Pleiotropism and Alzheimer's disease -- Primary prevention of Alzheimer's disease -- Secondary prevention of Alzheimer's disease -- Treatment mechanisms in mild to moderate Alzheimer's disease --Pleiotropic theory -- Part III. Rational basis versus strict scrutiny -- Dose-adherence and intent-to-treat.Alzheimer's diseaseChemotherapyAlzheimer's diseasePreventionAlzheimer's diseaseChemotherapy.Alzheimer's diseasePrevention.616.831061Friel Howard871918Frautschy SallyMiAaPQMiAaPQMiAaPQBOOK9910583361603321A paradigm shift to prevent and treat Alzheimer's disease1946736UNINA