05403nam 2200661 450 991058335810332120230120011423.00-7020-4268-4(CKB)2660000000010991(EBL)2072157(SSID)ssj0001535786(PQKBManifestationID)11860576(PQKBTitleCode)TC0001535786(PQKBWorkID)11502846(PQKB)11484270(MiAaPQ)EBC2072157(EXLCZ)99266000000001099120150701h20152015 uy 0engur|n|---|||||txtccrClinical equine oncology /Derek C. Knottenbelt, Janet C. Patterson-Kane, Katie L. SnaluneEdinburgh, [Scotland] :Elsevier,2015.©20151 online resource (715 p.)Description based upon print version of record.0-7020-4266-8 Includes bibliographical references at the end of each chapters and index.Front cover; Clinical Equine Oncology; Copyright page; Table of Contents; Preface; Acknowledgements; Dedication; Glossary; Specialist terms used in radiotherapy; I Basic principles of oncology; 1 Introduction; References; 2 The challenges and problems of equine oncological practice; References; 3 Tumour nomenclature; Introduction; Benign and malignant tumours; Benign tumours; Malignant tumours; Assessing tumour activity and behaviour in vitro and in vivo; Grading; Staging; TNM tumour staging; Measured/assessed parameters; Ann Arbor tumour staging; Reference; 4 Biology of tumour growthThe molecular and genetic (cellular) basis of cancerThe guardian of the genome: (T)p53 gene; DNA repair genes; Cell destruction; Apoptosis; Cellular evasion of apoptosis; Autophagy; Necrosis; Immune evasion; The role of calreticulin in tumour development; Cellular senescence; Cell interactions; Carcinogenesis; The Knudson hypothesis; The multistep carcinogenesis proposal; Chemical carcinogenesis; Radiation carcinogenesis; Microbiological/infectious agents of carcinogenesis; Other factors that promote tumour development; Tumour progression and proliferation; Angiogenesis; Tumour invasionThe stromal micro-environment of a tumourMetastasis; The genetic theory of metastasis; Routes of metastasis; The growth of tumours; The Gompertzian model; References; 5 Clinical effects of cancer in horses; Introduction; Clinical signs and consequences; Tissue type; Size/extent; Location; Number; Specific nature and pathological behaviour; Functionality; Duration; Differential diagnoses; Ulceration and infection; Physical appearance; References; 6 Paraneoplastic syndromes; Anorexia-cachexia and wasting syndromes; Tumour lysis syndrome; Hypercalcaemia/hypocalcaemia; Pyrexia; AnaemiaErythrocytosis (polycythaemia)Thrombocytosis/thrombocytopaenia; Hypoglycaemia; Hypercupraemia; Hyperfibrinogenaemia, hyperglobulinaemia and monoclonal gammopathy; Paraneoplastic pruritus; Paraneoplastic pemphigus and other dermatological paraneoplastic signs; Ulcerative coronitis; Paraneoplastic bullous stomatitis; Protein-losing enteropathy; Renal failure; Amyloidosis; Hypertrophic (pulmonary) osteopathy (Marie's disease); References; 7 Principles of diagnosis; Clinical investigations and specialized tests/imaging methods; Tissue sampling; Biopsy; Overview; Biopsy methods; Punch biopsyWedge biopsyPortional biopsy; Excisional/ablative biopsy; Fine-needle aspiration; Hollow-needle biopsy; Impression smears; Tissue fixatives; Haematology and biochemistry; Ultrasonography; Abdominocentesis/thoracocentesis; Total protein assay; Cytological assessment; Cerebrospinal fluid sampling; Bone marrow biopsy/aspiration; Bone marrow aspiration; Bone marrow biopsy; Technique; Radiography; X-ray computed tomography (CT); Magnetic resonance imaging (MRI); Scintigraphy; Laparoscopy/pleuroscopy/endoscopy; Technique; Limitations; Tumour markers; In vitro cell culture assessment; References8 Pathological methods in equine oncologyDiagnose common equine tumors accurately and find clinical information quickly! Clinical Equine Oncology describes the cellular basis of cancer and its etiopathogenesis, along with the principles of diagnosis, treatment, and management of cancer cases. This comprehensive resource offers more than just facts and diagrams - hundreds of detailed photographs make it easier to recognize and evaluate more than 50 types of tumors. It's useful to anyone working in the equine field, whether you're a veterinary surgeon, a practicing vet, equine dentist, or veterinary student. Written by a recognized exOncologyTumorsCancerTreatmentNeoplasmsveterinaryHorse DiseasesOncology.Tumors.CancerTreatment.Neoplasmsveterinary.Horse Diseases.636.10896994Knottenbelt Derek C.513506Patterson-Kane Janet C.Snalune Katie L.MiAaPQMiAaPQMiAaPQBOOK9910583358103321Clinical equine oncology2157095UNINA