02242nam 2200397 450 991058335470332120180710153856.00-12-809856-2(CKB)4340000000208900(MiAaPQ)EBC5106110(PPN)228029872(EXLCZ)99434000000020890020171117h20182018 uy 0engurcnu||||||||rdacontentrdamediardacarrierGERD a new understanding of pathology, pathophysiology, and treatment /Parakrama T. ChandrasomaLondon, England :Academic Press,2018.©20181 online resource (654 pages) illustrations (some color)0-12-809855-4 Includes bibliographical references at the end of each chapters and indexes.Definition of gastroesophageal reflux disease -- Present diagnosis and management of gastroesophageal and reflux disease -- Fetal and postnatal development of the esophagus and proximal stomach -- Histologic definition and diagnosis of epithelia in the esophagus and proximal stomach -- Definition of the normal state -- Definition of the gastroesophageal junction -- The normal lower esophageal sphincter -- The pathogenesis of early GERD -- Correlation of LES damage and GERD -- The effect of damage to the abdominal segement of the LES -- Columnar-lined esophagus -- Esophageal adenocarcinoma -- Progression of GERD at the clinical level -- Progression of GERD at a pathological level -- Molecular evolution of esophageal epithelial metaplasia -- Progression of GERD from the perspective of LES damage -- New pathologic test of LES damage -- New method of functional assessment of the LES -- Prediction of future progression of LES damage -- Proof of cencept of the new diagnostic method -- Application of the new method to present and future management of GERD.Gastroesophageal refluxGastroesophageal reflux.616.324Chandrasoma Para932152MiAaPQMiAaPQMiAaPQBOOK9910583354703321GERD2096921UNINA