04775nam 2200589 450 991058309250332120201211215713.00-7020-4537-30-444-53485-7(CKB)3710000000748369(EBL)4592086(MiAaPQ)EBC4592086(PPN)19553509X(EXLCZ)99371000000074836920160810h20162016 uy 0engur|n|---|||||rdacontentrdamediardacarrierNeuroimagingPart I /volume editors, Joseph C. Masdeu, R. Gilberto GonzalezAmsterdam, Netherlands :Elsevier,2016.©20161 online resource (724 p.)Handbook of Clinical Neurology ;Volume 135Description based upon print version of record.Includes bibliographical references at the end of each chapters and index.Front Cover; Neuroimaging Part I; Copyright; Handbook of Clinical Neurology 3rd Series; Foreword; Preface; Contributors; Contents of Part I; Contents of Part II; Section 1: Neuroimaging methods; Chapter 1: Computed tomography imaging and angiography - principles; Computed tomography imaging and angiography: principles; Introduction; Principles; Noncontrast computed tomography (NCCT); Computed tomography angiography (CTA); CT/CTA selected technical-clinical pearls and pitfalls; Stroke - technical pearls and pitfalls; Nontraumatic intracranial hemorrhage - technical pearls and pitfallsNew developments and future directions; Dual-energy CT (DECT); Iterative reconstruction algorithms; References; Chapter 2: MR imaging: deconstructing timing diagrams and demystifying k-space; Introduction; Spin localization; Spin synchronization; Concept of an echo and k-space; A closer look at image space and k-space; Image detection and resolution considerations; Parallel imaging; A word about contrast; k-Space mapping strategies; Conclusions; References; Chapter 3: Volumetric and fiber-tracing MRI methods for gray and white matter; Introduction; Brain macrostructure and microstructureQuantitative volumetric brain analysis: segmentation; Structural segmentation methods; Imaging requirements; Sources of error; Analysis of brain segmentation results; Volumetric analysis; Surface analysis; Segmentation methods: practical approaches; Segmentation workflow; Brain segmentation systems; Applications of brain segmentation analysis; Evaluation of normal aging; Neurodegenerative disease; Alzheimer's disease; Frontotemporal dementia; Epilepsy; Quantitative analysis of white-matter integrity: diffusion and tractographic analysis; Introduction; Local diffusion analysisRegional diffusion analysis: tractography; Diffusion MRI methods; Application of diffusion MRI in the evaluation of white-matter integrity; Local dMRI measures of white-matter integrity and injury; Local measures of dMRI in demyelinating disease; Local measures of dMRI changes in normal aging; Local measures of dMRI in neurodegenerative disease; Regional measures of white-matter integrity: tractography; Tractography: axonal patterning; Tractography: brain connectivity; Tractography: applications; Diffusion MRI and tractography methods: practical approachesDiffusion MRI and tractography workflows; Diffusion MRI and tractography systems; Future developments; Summary; References; Chapter 4: Functional magnetic resonance imaging; Introduction; Physiologic principles underlying bold fMRI; Metabolic and hemodynamic signals are surrogates for neural activity; Neurometabolic and neurovascular coupling; Synaptic activity dominantly drives signaling-related energy metabolism; Classic model: neural activity is linearly coupled to CMRGlc, CMRO2, and CBF; Experiment: at rest neural activity is linearly coupled to CMRO2, CMRGlc, and CBFExperiment: with activation, neural activity is nonlinearly coupled to CMRGlc and CBF, but nearly linearly coupled to CMRO2Handbook of clinical neurology ;Volume 135.Nervous systemImagingNervous systemDiseasesImagingNervous System DiseasesdiagnosisNeuroimagingmethodsNervous systemImaging.Nervous systemDiseasesImaging.Nervous System Diseasesdiagnosis.Neuroimagingmethods.616.804754Masdeu Joseph C.Gonzalez R. GilbertoMiAaPQMiAaPQMiAaPQBOOK9910583092503321Neuroimaging1751159UNINA