03265nam 2201009z- 450 991058021600332120231214132924.0(CKB)5690000000011927(oapen)https://directory.doabooks.org/handle/20.500.12854/87447(EXLCZ)99569000000001192720202207d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierCell Biology of GalectinsBaselMDPI - Multidisciplinary Digital Publishing Institute20221 electronic resource (202 p.)3-0365-4448-8 3-0365-4447-X Galectins are a family of soluble beta-galactoside-binding proteins with diverse glycan-dependent and glycan-independent functions outside and inside the cell. There are sixteen recognized mammalian galectin genes, and their expression profiles are very different between cell types, tissues, and species. This Special Issue covers recent progress in the field of the cell biology of galectins, relevant concepts of galectin regulatory mechanisms, and biomedical aspects of these unique multifunctional proteins.Research & information: generalbicsscBiology, life sciencesbicsscgalectin-7p53MMP-9cancergain-of-functionvasculaturegene expressiontube formationsproutingVEGFintegrinsgalectinextracellular matrixmicroenvironmentYersinia enterocoliticaYopPGalectin-1nitric oxidemacrophagesepithelial tissuesapoptosistargetinginhibitorsβ-hairpinβ-sandwichblood group Blectinsugar codeLGALS16placentabrain tissuescell differentiationtranscription factormiRNAgalectin-3cardiac fibrosisheart failureatrial fibrillationchronic inflammationMMPsmicroRNAslncRNAspectinstructure and functionbioactive polysaccharidesgalectin-3 inhibitiongalacto-oligosaccharidesgalectinsintestinal epithelial cellsβ-3'galactosyllactoseimmunomodulationmucosal immunityO-GlcNAcunconventional secretionextraembryonic endodermResearch & information: generalBiology, life sciencesTimoshenko Alexanderedt1326276Timoshenko AlexanderothBOOK9910580216003321Cell Biology of Galectins3037248UNINA