01158nas 2200385- 450 991086919550332120240201213018.02514-9334(DE-599)ZDB2929765-5(OCoLC)1018198055(CKB)4100000001587884(CONSER)--2018204954(EXLCZ)99410000000158788420170504a20189999 --- aengur|||||||||||txtrdacontentcrdamediacrrdacarrierCollection and curationBingley :Emerald Publishing, United Kingdom,[2018]-Refereed/Peer-reviewed2514-9326 0160-4953 Collection development (Libraries)PeriodicalsCollection development (Libraries)fast(OCoLC)fst00867172Periodicals.fastPeriodicals.lcgftCollection development (Libraries)Collection development (Libraries)025.21JOURNAL9910869195503321Collection and curation2368396UNINA04635nam 2201369z- 450 991058021460332120220706(CKB)5690000000011942(oapen)https://directory.doabooks.org/handle/20.500.12854/87508(oapen)doab87508(EXLCZ)99569000000001194220202207d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierToxic Metals, Chronic Diseases and Related CancersBaselMDPI - Multidisciplinary Digital Publishing Institute20221 online resource (318 p.)3-0365-4171-3 3-0365-4172-1 Long-term exposure to environmental toxicants is estimated to account for 70-90% of the risks of acquiring chronic ailments. Presently, chronic kidney disease and infertility affect a significant proportion of the world population, while research data indicate that exposure to toxic metals may contribute to the looming statistics. Alarming evidence suggests that exposure to the heavy metal cadmium may affect every stage of life, and exposure in early life may determine susceptibility to certain diseases in adulthood. Prevention of these outcomes requires avoidance of further environmental contamination, minimization of exposure, and reduction of toxic metals in food crops to the lowest achievable levels.Public health and preventive medicinebicssca follow-up studyaluminum chlorideautopsy tissuesbirth weightblood leadblood lead levelboatyardcadmiumcase-control studycellular immunitycerebrovascular accidentchildhoodchildrenchronic kidney diseaseConstantí (Catalonia, Spain)creatinine clearancecreatinine excretiondiabetesdietdiet patterndynamin-related protein 1 (Drp1)elevated liver enzymesendocytosisfarmerfishing communityflow cytometryfoodgenotoxicityglomerular filtrationglomerular filtration rateglucose response mechanismhairhazardous waste incineratorheavy metalheavy metalshexavalent chromium [Cr(VI)]humoral munityhyperglycemiahyperinsulinemiahyperlipidemiaimmunosuppressioninsulinkidneykidney functionleadlead poisoninglead weightslifetime cadmium intakelipid profileslipogenicMediterranean dietmercurymetallothioneinminimal modelmitochondrial fragmentationmitochondrial respiratory chain complex I (MRCC I)Monte Carlo simulationmortalityN-acetyl-β-d-glucosaminidasen/anephron massnephrotoxicityobesogenOGTTphagocytosispregnancypreterm birthproximal tubule epithelial cellsPTWI (provisional tolerable monthly intake)rare earth elementratsreactive oxygen species (ROS)renal diseasesreproductionstroketemporal trendstesticular and ovarian structurethreshold limittolerable intake leveltoxic metalstrace elementsTrace elementsTWI (tolerable weekly intake)urinary cadmiumβ-cell toxicityβ2-microglobulinPublic health and preventive medicineSatarug Soisungwanedt1302837Satarug SoisungwanothBOOK9910580214603321Toxic Metals, Chronic Diseases and Related Cancers3037246UNINA