04939nam 2201321z- 450 991058021260332120231214133459.0(CKB)5690000000011962(oapen)https://directory.doabooks.org/handle/20.500.12854/87516(EXLCZ)99569000000001196220202207d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierOncologic Thermoradiotherapy: Need for Evidence, Harmonisation, and InnovationBaselMDPI - Multidisciplinary Digital Publishing Institute20221 electronic resource (346 p.)3-0365-4532-8 3-0365-4531-X The road of acceptance of oncologic thermotherapy/hyperthermia as a synergistic modality in combination with standard oncologic therapies is still bumpy. This is partially due to the lack of level I evidence from international, multicentric, randomized clinical trials including large patient numbers and a long term follow-up. Therefore we need more level I EVIDENCE from clinical trials, we need HARMONISATION and global acceptance for existing technologies and a common language understood by all stakeholders and we need INNOVATION in the fields of biology, clinics and technology to move thermotherapy/hyperthermia forward. This is the main focus of this reprint. In this reprintyou find carefully selected and peer-reviewed contributions from Africa, America, Asia, and Europe. The published papers from leading scientists from all over the world covering a broad range of timely research topics might also help to strengthen thermotherapy on a global level.Oncologic ThermoradiotherapyMedicinebicsscOncologybicsscperfusion estimationtemperature monitoringconductivity reconstructionsystems medicineimmune system in silicoperceptronantigen patterndanger signalfractionationimmune responsehead and neck cancerhyperthermiareirradiationtreatment outcomehyperthermia treatment planningadaptive planningtemperature optimizationlow-middle-income group countriescancerradiotherapychemotherapyrecurrent breast cancerscervical cancerhead and neck cancerscost-effectivemeta-analysisintensity-modulated radiotherapyprostate cancerthermal dosethermometric parameterspreclinical dataclinical evidencemodulated electro-hyperthermiaabscopal effectlocally advanced cervical cancerresource-constrained settingradiosensitiserrectal cancerchemoradiotherapytumour controlloco-regional hyperthermiaoncologycellular selectionbioelectromagneticscomplexityimmune-effectsmoderate hyperthermiadeep hyperthermiaradiative hyperthermiapatterns of carereimbursementregional hyperthermianeoadjuvant chemoradiationsurvivalinducedbrachytherapyprostatic neoplasmsinterstitial hyperthermiatreatment plan optimizationprostatethermoradiotherapylinear quadratic modelbiological modelingthermal dosimetryhypoxiaradiation therapyreoxygenationperfusionoxygen consumption ratelocal tumor controlbiomarkerimmune phenotypehyperthermia treatment sequencebreast cancerimmune checkpoint moleculesdendritic cell activationMedicineOncologyBodis Stephanedt1326273Ghadjar PirusedtVan Rhoon Gerard CedtBodis StephanothGhadjar PirusothVan Rhoon Gerard CothBOOK9910580212603321Oncologic Thermoradiotherapy: Need for Evidence, Harmonisation, and Innovation3037243UNINA