04511nam 2201129z- 450 991058020910332120220706(CKB)5690000000011997(oapen)https://directory.doabooks.org/handle/20.500.12854/87502(oapen)doab87502(EXLCZ)99569000000001199720202207d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierMechanisms and Novel Therapeutic Approaches for Gynecologic CancerBaselMDPI - Multidisciplinary Digital Publishing Institute20221 online resource (258 p.)3-0365-4383-X 3-0365-4384-8 This book-entitled "Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer"-was edited as a Special Issue of Biomedicines, focusing on basic research such as genomics, epigenomics, and proteomics, as well as clinical research in the field of gynecologic oncology. The number of patients with gynecological cancer has been increasing worldwide due to its high lethality and lack of early detection tools and effective therapeutic interventions. In this regard, basic research on its pathophysiology and novel molecular targeting intervention is required to improve the prognosis of gynecologic cancer. This book contains 13 papers, including 8 original research papers and 5 reviews focusing on the basic research of gynecologic oncology. The reader can learn about state-of-the-art research and obtain extensive knowledge of the current advances in the field of gynecologic oncology. It is my hope that this book contributes towards the progress of gynecologic oncology.Public health and preventive medicinebicsscadoptive immunotherapyanti-angiogenic therapyaryl hydrocarbon receptorBEN (BANP, E5R and NAC1) domainbiological planningbiomarkersborderline ovarian tumorsBRCA1 mutant ovarian cancercancer progressionCD44cervical cancercervical neoplasiachimeric antigen receptorclear cell carcinomadifferentially expressed genesDNA damage responseDNA mismatch repair (MMR)drug repurposingendometrial cancerendometrial carcinomaendometrioid endometrial cancerepithelial ovarian cancerepithelial ovarian cancersepithelial-mesenchymal transitionexosomegene ontologygynecological cancerHDR brachytherapyhuman cytomegalovirusimmune checkpoints inhibitorsimmune micro-environmentimmunohistochemistryimmunosuppressionin vivo dosimetryinflammationintegrative analysisinterventional radiotherapyisothermal titration calorimetry (ITC)liquid biopsylong-term survivalmelanoma treatmentmicrosatellite instabilitymiRNAmismatch repair deficiencyMMR deficient (dMMR)n/ananocarriersNK cellsnon-coding RNAsnucleus accumbens-associated protein 1 (NAC1)ovarian cancerp16 proteinpGSK3βPLA2G7)platelet-activating factor acetylhydrolase (PAF-AHprognosissequence-specific DNA-binding proteinsolution NMR structuresomatic mutationtargeted therapytestinvaginal melanomavaginal-cuff brachytherapyvulvar melanomaWnt signalingβ-cateninPublic health and preventive medicineNakayama Naomiedt1326272Nakayama NaomiothBOOK9910580209103321Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer3037242UNINA