04478nam 2201105z- 450 991058020910332120231214132952.0(CKB)5690000000011997(oapen)https://directory.doabooks.org/handle/20.500.12854/87502(EXLCZ)99569000000001199720202207d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierMechanisms and Novel Therapeutic Approaches for Gynecologic CancerBaselMDPI - Multidisciplinary Digital Publishing Institute20221 electronic resource (258 p.)3-0365-4383-X 3-0365-4384-8 This book—entitled “Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer”—was edited as a Special Issue of Biomedicines, focusing on basic research such as genomics, epigenomics, and proteomics, as well as clinical research in the field of gynecologic oncology. The number of patients with gynecological cancer has been increasing worldwide due to its high lethality and lack of early detection tools and effective therapeutic interventions. In this regard, basic research on its pathophysiology and novel molecular targeting intervention is required to improve the prognosis of gynecologic cancer. This book contains 13 papers, including 8 original research papers and 5 reviews focusing on the basic research of gynecologic oncology. The reader can learn about state-of-the-art research and obtain extensive knowledge of the current advances in the field of gynecologic oncology. It is my hope that this book contributes towards the progress of gynecologic oncology.Public health & preventive medicinebicsscnucleus accumbens-associated protein 1 (NAC1)BEN (BANP, E5R and NAC1) domainsequence-specific DNA-binding proteinsolution NMR structureisothermal titration calorimetry (ITC)human cytomegalovirusovarian cancercancer progressioninflammationimmunosuppressionendometrial carcinomaimmune micro-environmentimmune checkpoints inhibitorsmicrosatellite instabilitymismatch repair deficiencyplatelet-activating factor acetylhydrolase (PAF-AHPLA2G7)BRCA1 mutant ovarian cancerWnt signalingpGSK3ββ-cateninprognosisvulvar melanomavaginal melanomatargeted therapygynecological cancermelanoma treatmentgene ontologyepithelial ovarian cancersborderline ovarian tumorsdifferentially expressed genesaryl hydrocarbon receptorepithelial-mesenchymal transitionintegrative analysistestinp16 proteincervical cancercervical neoplasiaimmunohistochemistrychimeric antigen receptorCD44adoptive immunotherapyNK cellsepithelial ovarian cancerDNA damage responsesomatic mutationclear cell carcinomaendometrioid endometrial cancerDNA mismatch repair (MMR)MMR deficient (dMMR)long-term survivalexosomemiRNAbiomarkersliquid biopsyinterventional radiotherapyvaginal-cuff brachytherapyHDR brachytherapyin vivo dosimetryendometrial cancerbiological planningdrug repurposingnon-coding RNAsnanocarriersanti-angiogenic therapyPublic health & preventive medicineNakayama Naomiedt1326272Nakayama NaomiothBOOK9910580209103321Mechanisms and Novel Therapeutic Approaches for Gynecologic Cancer3037242UNINA