04736nam 2201321z- 450 991058020900332120220706(CKB)5690000000011998(oapen)https://directory.doabooks.org/handle/20.500.12854/87506(oapen)doab87506(EXLCZ)99569000000001199820202207d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierBabesia and Human BabesiosisBaselMDPI - Multidisciplinary Digital Publishing Institute20221 online resource (294 p.)3-0365-4472-0 3-0365-4471-2 Babesiosis, caused by tick-transmitted intraerythrocytic parasites (Babesia spp.), occurs worldwide. The disease mainly affects livestock, but records of infections in humans are increasing, and the disease is considered to be emerging worldwide. This book provides a comprehensive and holistic view of Babesia species that can infect humans. Numerous experts analyze, in detail, basic aspects of the biology of Babesia, the pathology of the babesiosis highlighting the pathogenesis of babesiosis in sickle cell, the eco-epidemiology of tick vectors and the impact of climate change on them, the current status, and future prospects for laboratory diagnosis and measures to prevent transfusion transmission. The book also focused on unidentified Babesia parasites that continue to emerge, most likely from wildlife, for which neither tick vector species nor vertebrate reservoir host species are currently known. Lastly, current and new therapies for infected patients, in vitro and in vivo culture systems for antibabesial evaluation and measures to prevent infections are also considered.Epidemiology and Medical statisticsbicsscMedicine and Nursingbicsscama-1antibody-based assaysantigenapicomplexaaspartyl proteaseatovaquoneBabesiaBabesia bigeminaBabesia bovisBabesia capreoliBabesia divergensBabesia duncaniBabesia microtiBabesia sp.Babesia sp. MO1Babesia venatorumbabesiosisbiological cycleblood transfusionBmIPA48BMR1_03g00960case surveillanceclimateclinical casesColombiadiagnosisdiversityDMEM-F12ecologyendochin-like quinolones (ELQs)epidemiologyerythrocytesEuropean babesiosisexperimental modelsexperimental transmissionfallow deerglobal warmingglycosylphosphatidylinositolhaemoglobinopathieshemolysishost blood analysishuman babesiosishuman riskimmunoepidemiologyin vitro cultureIxodes ricinusIxodes scapularisixodid ticksmultiplex detectionn/aNantucket Islandnext generation sequencingnucleic acid testsparasiteparasite identitypeptidasesphylogenetic analysisphylogenypiroplasmpiroplasmid rhoptry-associated protein-1 (pRAP-1)piroplasmidaplasmepsinpreventionprotein structurerap-1ared deerscreeningsickle-cell anemiaTheileriatherapeutic drugstherapytickstreatmentvirulenceEpidemiology and Medical statisticsMedicine and NursingMontero Estrellaedt1304519Gray JeremyedtLobo Cheryl AnnedtGonzález Luis MigueledtMontero EstrellaothGray JeremyothLobo Cheryl AnnothGonzález Luis MiguelothBOOK9910580209003321Babesia and Human Babesiosis3027519UNINA