00952nam0-22003251i-450-99000090426040332120091104125529.00-7503-0840-0000090426FED01000090426(Aleph)000090426FED0100009042620030226d2002----km-y0itay50------baengGBa-------001yyEvaluating the measurement uncertaintyfundamentals and practical guidanceIgnacio LiraBristolInstitut of Physics Pub.2002XVI,243 p.ill.24 cmSeries in measurement science and technologyMisure530.8Lira,Ignacio44035ITUNINARICAUNIMARCBK99000090426040332110 D I 248DIEL 2976DINELDINELEvaluating the measurement uncertainty357513UNINA00919nam0-22003251i-450 99000082676040332120190225114933.00-7167-0334-3000082676FED01000082676(Aleph)000082676FED0100008267620001010d1973----km-y0itay50------baengy-------001yyGravitationCharles W. Misner, Kip S. Thorne, John Archibald WheelerSan FranciscoW.H. Freeman and Compa ny1973XXVI , 1279 p. tav. 25 cm531.14Misner,Charles W.40400Thorne,Kip S.40401Wheeler,John Archibald40349ITUNINARICAUNIMARCBK99000082676040332102 61 A 83772FINBNFINBNGravitation44639UNINAING0107115 am 2201657 n 450 9910568199903321202201032-84867-737-610.4000/books.pufc.42875(CKB)4100000012875406(FrMaCLE)OB-pufc-42875(oapen)https://directory.doabooks.org/handle/20.500.12854/86229(PPN)263271048(EXLCZ)99410000001287540620220517j|||||||| ||| 0freuu||||||m||||txtrdacontentcrdamediacrrdacarrierPaysages et environnement De la reconstitution du passé aux modèles prospectifs /Didier GalopBesançon Presses universitaires de Franche-Comté20221 online resource (489 p.) Annales littéraires2-84867-445-8 Organisé dans le cadre du Réseau Thématique Pluridisciplinaire « Paysage et Environnement » du CNRS et dans le but affiché de favoriser les échanges disciplinaires ainsi que la diffusion des recherches de jeunes chercheurs, le colloque « Paysages et environnement. De la reconstitution du passé aux modèles prospectifs » a rassemblé une large communauté scientifique ainsi que de nombreux représentants d’organismes publics impliqués dans l’étude, la gestion ou la conservation des paysages et de l’environnement. Articulé autour de trois thèmes principaux : « Le passé : reconstitutions, transmission et nouveaux indicateurs des dynamiques environnementales » ; « Représentations sociales et formes de l’action » et enfin « Modélisation, scénarios prospectifs et rétro-prospectifs », ce volume réunit trente-six articles. Il brosse un tableau représentatif du dynamisme et de la richesse des recherches menées aujourd’hui dans ces domaines, qu’il s’agisse d’études mono-disciplinaires ou d’approches interdisciplinaires intégrées. Les contributions, originales pour la plupart, résultent de travaux ou de programmes de recherches collectifs faisant appel à des approches traditionnelles ainsi qu’à des démarches innovantes visant à la reconstitution des environnements et des paysages du passé mais aussi, dans le cadre d’approches prospectives, à la détermination de leurs évolutions futures.ArchaeologyenvironnementpaysagearchéologieenvironnementpaysagearchéologieArchaeologyenvironnementpaysagearchéologieAkköprü Ebru1331163Alard Didier1331164Alexandre Frédéric1288309Allignol Françoise418330Andrieu Julien1331165Antonio Lopez-Saez José1331166Argant Jacqueline1295912Astrade Laurent1331167Bal Marie-Claude1314165Ballut Christèle1272926Bargeot Lionel1331168Baron Sandrine1331169Beaupied David1331170Berger Jean-François1234136Bernigaud Nicolas1331171Bleu Stéphane1331172Bouby Laurent1293582Boutterin Clément1331173Bretagnolle François1331174Brun Cécile1331175Brunet Didier1331176Brunon Hervé754562Brunstein Daniel1331177Cador Jean-Michel1331178Carignan Jean1331179Carpentier Vincent1295077Chambaud François1331180Chevalier Bruno1331181Christol Aurélien1331182Clet-Pellerin Martine1331183Couderchet Laurent1331184Dessaint Fabrice1331185De Champsavin Sophie1331186Dogu Ali Fuat1331187Dournel Sylvain1302637Droeven Émilie1331188Dutoit Thierry1294763Edouard Jean-Louis1323591Ertlen Damien1325273Fajon Philippe1302525Fontugne Michel1331189Gaby Grégoire1331190Galop Didier1299202Garnier Emmanuel1289605Gaucher Grégory1331191Gautreau Pierre1287588Germaine Marie-Anne1331192Goepp Stéphanie1331193Gourmelon Jérôme1331194Guillerme Sylvie317870Hanus Philippe1331195Hauger Karl1331196Henry Frédéric1331197Hinnewinkel Christelle317866Houet Thomas1331198Hubert-Moy Laurence1331199Jacob Nicolas419893Karabiyikoglu Mustafa1331200Kuzucuoglu Catherine531905Leciak Élisabeth1331201Lespez Laurent1283438Le Lay Yves-François1331202Lion Marie1331203Loudiyi Salma1076268Magnin Frédéric1314177Mai Bui Thi1331204Marcigny Cyril1283934Martin Sophie1284603Maury Virginie1331205Mazagol Pierre-Olivier1331206Mering Catherine1331207Millet Laurent1308933Miramont Cécile436272Monique Fort1331208Moreau Myrtille1331209Mouralis Damase1331210Muller Serge-D1331211Perrette Yves1330776Pesquet Gilles1331212Ploquin Alain1325008Porteret Jérôme1331213Prat Béatrice1331214Richard Hervé1307203Rivière-Honegger Anne1331215Robert Sandrine618758Rochel Xavier1331216Royet Elvyre1331217Royet Robert1282835Salvador Pierre-Gil1294619Schwartz Dominique1331218Sittler Benoit1331219Sivan Olivier1325297Talon Brigitte1323633Thinon Michel1331220Touflan Philippe1331221Valleteau Sophie1331222Vigneau Thomas1331223Zorer Halil1331224Galop Didier1299202FR-FrMaCLEBOOK9910568199903321Paysages et environnement3040270UNINA03406oam 2200493 450 991013708820332120230621141059.09782889196623 (ebook)(CKB)3710000000824755(oapen)https://directory.doabooks.org/handle/20.500.12854/42865(EXLCZ)99371000000082475520191103c2015uuuu uu |engurmn|---annantxtrdacontentcrdamediacrrdacarrierCellular and phenotypic plasticity in cancer[electronic resource] /edited by Petranel Theresa Ferrao, Andreas Behren, Robin Andersonand Erik ThompsonFrontiers Media SA2015France :Frontiers Media SA,20151 online resource (77 pages) illustrationsFrontiers Research TopicsIncludes bibliographical references.The process of Epithelial-Mesenchymal-Transition (EMT) is known to result in a phenotype change in cells from a proliferative state to a more invasive state. EMT has been reported to drive the metastatic spread of various cancers and has also been associated with drug resistance to cytotoxics and targeted therapeutics. Recently phenotype switching akin to EMT has been reported in non-epithelial cancers such as metastatic melanoma. This process involves changes in EMT-Transcription Factors (EMT-TFs), suggesting that phenotype-switching may be common to several tumour types. It remains unclear as to whether the presence of both Epilthelial-like and Mesenchymal-like cells are a pre-requisite for phenotype switching within a tumour, how this heterogeneity is regulated, and if alteration of cell phenotype is sufficient to mediate migratory changes, or whether drivers of cell migration result in an associated phenotype switch in cancer cells. Similarly it has yet to be clarified if cells in an altered phenotype can be refractory to drug therapy or whether mediators of drug resistance induce a concurrent phenotypic change. Little is known today about the underlying genetic, epigenetic and transient changes that accompany this phenotypic switch and about the role for the tumor micro-environment in influencing it. Hence this is currently an area of speculation and keen interest in the Oncology field with wide-ranging translational implications. In this Frontiers Research Topic, we discuss our current understanding of these concepts in various cancer types including breast cancer, colorectal cancer and metastatic melanoma. This topic covers how these processes of cellular and phenotypic plasticity are regulated and how they relate to cancer initiation, progression, dormancy, metastases and response to cytotoxics or targeted therapies.CancercrosstalkImmune SystemPhenotype-switchingplasticityExosomesEMTTherapy-resistancesignallingheterogeneityCancerCancerPetranel Theresa Ferraoauth1365478Andreas BehrenauthErik ThompsonauthRobin AndersonauthUkMaJRU9910137088203321Cellular and phenotypic plasticity in cancer3387417UNINA