05511nam 2201489z- 450 991056647800332120231214133452.0(CKB)5680000000037600(oapen)https://directory.doabooks.org/handle/20.500.12854/80967(EXLCZ)99568000000003760020202205d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierInnovations in the Integrated Management of Breast CancerBaselMDPI - Multidisciplinary Digital Publishing Institute20221 electronic resource (278 p.)3-0365-3802-X 3-0365-3801-1 Breast cancer is acknowledged as an international priority in healthcare. It is currently the most common cancer in women worldwide, with demographic trends indicating a continuous increase in incidence. Over the years, increasing efforts and resources have been devoted to the search for a systematic and optimized strategy in breast cancer diagnosis and treatment. Today, the Breast Unit model is considered the gold standard in order to ensure optimal patient-centered and research-based clinical services through multidisciplinary and integrated management.Surgical treatment has gradually evolved toward less aggressive approaches with the adoption of new therapeutic strategies. The evolution of evidence-based guidelines in such leading disciplines as radiation and medical oncology has led to a steady improvement in survival rates. This Special Issue will highlight innovations in the integrated management of breast cancer, their potential advantages, and the many open issues that still need to be properly defined and addressed.MedicinebicsscPharmacologybicsscmetastatic breast cancerbreast surgeryimmune systemmetabolic derangementsprecision medicineintegrated therapiesadvanced breast cancermTOR inhibitorCDK4/6 inhibitorendocrine resistancebreast cancerpregnancychemotherapytailoringpersonalizationDataMartreal world datapredictive modelhealthcarebreast-conserving surgerynon-palpable breast lesionsimage-guided localizationpreoperative breast localizationbreast ultrasoundlarge databasestandardized data collectionnetworksnipple-sparing mastectomyimmediate breast reconstructionacellular dermal matrix (ADM)aesthetic and oncological outcomesquality of liferare breast cancerosteoclast-like giant cellsgene profilingOncotype Dxadjuvant treatmentneoadjuvant chemotherapysentinel lymph nodesystemic treatmentlocally advanced breast cancermini-invasive treatmentliver metastaseshepatic surgerypersonalized medicinesarcopeniaphysical performancefrailtyolder cancer patientsclinical trialpatient enrollmentartificial intelligencemachine learninglung canceroncologyweb appconventional CT and CT angiographyDIEP flap planningmultidisciplinary treatmentevidence-based medicinepersonalized treatmentoncological outcomespatient quality of lifenormal breastbreast pathologyhormone receptorhormone expressionlymphedemalymphaticovenous anastomosisvascularized lymph node transferlymphatic microsurgeryradiotherapyoligometastatic breast cancerlocoregional therapyCDK4/6 inhibitorsmultidisciplinaryAMHovarian reservepregnancy desiresubtypes breast cancermiRNAsbreast cancer treatmentnext-generation-sequencingtarget therapyold agesurvivalvitamin Dductal breast cancerin situ breast cancerlobular breast cancerhistologyMedicinePharmacologyFranceschini Gianlucaedt1326260Sanchez Alejandro MartinedtMasetti RiccardoedtFranceschini GianlucaothSanchez Alejandro MartinothMasetti RiccardoothBOOK9910566478003321Innovations in the Integrated Management of Breast Cancer3037228UNINA