05245nam 2201357z- 450 991056647510332120220506(CKB)5680000000037628(oapen)https://directory.doabooks.org/handle/20.500.12854/81151(oapen)doab81151(EXLCZ)99568000000003762820202205d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierPersonalized Medicine in the Field of Inflammatory Skin DisordersBaselMDPI - Multidisciplinary Digital Publishing Institute20221 online resource (262 p.)3-0365-3574-8 3-0365-3573-X Skin inflammation is associated with a wide range of conditions which represent major health issues worldwide. Skin and mucosal surfaces represent the primary interface between the human body and the environment, susceptible to numerous factors whose action results in diseases produced by chemical substances, mechanical trauma, microbial agents, radiation, etc. Inflammation, a complex network of interactions between soluble molecules and cells, represents the main modality of the skin's response to injuries. Numerous studies have revealed close links between chronic inflammation, oxidative stress, and carcinogenesis. Chronic inflammation induces the activation of various cell types and an increase in the production of reactive oxygen species, promoting the initiation of a malignant process. Identifying specific biomarkers is essential for understanding molecular mechanisms and developing therapies appropriate to the patient's characteristics.Personalized medicine is an emerging field of medicine that has the potential to predict which therapy will be safe and efficacious for specific patients using an individual's genetic profile to guide decisions regarding the diagnosis, treatment, as well as prevention of disease. This book gathers articles that present recent advancements in research involving the mechanisms that underlie the development of inflammatory skin disorders, skin and mucosal inflammation in general.Medicine and NursingbicsscAKalginateandrogenic alopeciaantioxidative stress strategiesatopic dermatitisautoinflammatory diseasebiomarkerbiomarkersbiomaterialC57 BL/6 micecalumenincannabinoidscarbohydrate oxidationCD36clinical trialcommercially availablecomorbiditiescorticosteroidsCOVID-19cSCCcutaneous melanomacyclosporinecytohesin 2DNA oxidationdressingdrug resistanceeczemaepigenetic regulationepigenetic therapyestrogenevidence-based medicinefibersgut-lung-skin barrierhair densityhalo nevihydrogelIgYimiquimodimmune responseimmune-mediated skin diseasesimmunosuppressioninflammationinflammatory biomarkersJAK inhibitorslipid peroxidationlong-chain fatty acidslupus nephritismenopausemeta-analysisn/ananofibersoxidized proteinsplatelet-rich plasmaprevalenceproteome analysispsoriasispsoriasis vulgarispsoriatic dermatitispyoderma gangrenosumrisk factorsS100A6sea-buckthorn seed oilsialidasesialylationsialyltransferasesignaling pathwaysskin conditions and systemic inflammatory diseasesskin dysplastic keratinocytesskin tumorSR-B2Sutton nevisystematic reviewsystemic lupus erythematoussystemic sclerosistarget therapytherapeutic targetsUVAwound carewound healingMedicine and NursingTampa Mirceaedt1279506Neagu MonicaedtCaruntu ConstantinedtGeorgescu Simona RoxanaedtTampa MirceaothNeagu MonicaothCaruntu ConstantinothGeorgescu Simona RoxanaothBOOK9910566475103321Personalized Medicine in the Field of Inflammatory Skin Disorders3015522UNINA