04632nam 2201045z- 450 991056646360332120220506(CKB)5680000000037745(oapen)https://directory.doabooks.org/handle/20.500.12854/81047(oapen)doab81047(EXLCZ)99568000000003774520202205d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierIdentification and Characterization of Genetic Components in Autism Spectrum Disorders 2020BaselMDPI - Multidisciplinary Digital Publishing Institute20221 online resource (204 p.)3-0365-3611-6 3-0365-3612-4 The Identification of the Genetic Components of Autism Spectrum Disorders 2020 will be a useful resource for laboratory and clinical scientists, translational-based researchers, primary healthcare providers and physicians, psychologists/psychiatrists, neurologists, developmental pediatricians, clinical geneticists, teachers, special educators, and caregivers involved with individuals who have autism spectrum disorders (ASD), with the goal to translate information directly to the clinical, education and home settings. Other professionals, students at all levels, and families who are interested in this important neurodevelopmental disorder will find this textbook of value by obtaining a better awareness of the causes, testing, and understanding of genetic components leading to autism, and research that may open avenues for treatment with new approaches. This textbook includes nine chapters divided into three sections (clinical, genetics, other) written by experts in the field dedicated to genetics research and clinical care, description, and treatment by generating reviews for ASD and related disorders. These chapters include information on discoveries, risk factors, causation, diagnosis, treatment, and phenotyping with characterization of genomic or genetic factors and the environment, as genetics play an important role in up to 90% of individuals with autism via over 800 currently recognized genes.Biology, life sciencesbicsscGenetics (non-medical)bicsscResearch & information: generalbicssc15q11.2 BP1-BP2 deletion22q13.3 duplicationASDassessmentASSRauditory event-related potentialauditory steady-state responseautismautism spectrum disorderautism spectrum disordersautism spectrum disorders (ASDs)bioinformaticsbiomarkerBroader Autism PhenotypeBurnside-Butler syndromeCACNA1CcausesCaV1.2clinical decision support systems (CDSSs)clinical findingsCNVcognitiondental enamel defectdisease biomarkersDNA methylationenvironmental factorsepigenetic factorsERPexome sequencinggene fusiongeneticgenetic factorsgeneticsgenomic characterizationheterogeneityhuman geneticsintellectual disabilitiesinteractomicsmedicationsmetabolomicsmultiplex familyneuropsychiatric behavior developmentpervasive developmental disorderpharmacogenomicsphenotypic subgroups stratified by ASD severitypost-synaptic densityprotein-protein interactionproteomicsSHANK3short QT syndromesimplex familiesSNPsubgroup-associated genes and biological functionssyndromestreatmentBiology, life sciencesGenetics (non-medical)Research & information: generalButler Merlin Gedt1261076Butler Merlin GothBOOK9910566463603321Identification and Characterization of Genetic Components in Autism Spectrum Disorders 20203021929UNINA