04617nam 2201033z- 450 991056646360332120231214133240.0(CKB)5680000000037745(oapen)https://directory.doabooks.org/handle/20.500.12854/81047(EXLCZ)99568000000003774520202205d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierIdentification and Characterization of Genetic Components in Autism Spectrum Disorders 2020BaselMDPI - Multidisciplinary Digital Publishing Institute20221 electronic resource (204 p.)3-0365-3611-6 3-0365-3612-4 The Identification of the Genetic Components of Autism Spectrum Disorders 2020 will be a useful resource for laboratory and clinical scientists, translational-based researchers, primary healthcare providers and physicians, psychologists/psychiatrists, neurologists, developmental pediatricians, clinical geneticists, teachers, special educators, and caregivers involved with individuals who have autism spectrum disorders (ASD), with the goal to translate information directly to the clinical, education and home settings. Other professionals, students at all levels, and families who are interested in this important neurodevelopmental disorder will find this textbook of value by obtaining a better awareness of the causes, testing, and understanding of genetic components leading to autism, and research that may open avenues for treatment with new approaches. This textbook includes nine chapters divided into three sections (clinical, genetics, other) written by experts in the field dedicated to genetics research and clinical care, description, and treatment by generating reviews for ASD and related disorders. These chapters include information on discoveries, risk factors, causation, diagnosis, treatment, and phenotyping with characterization of genomic or genetic factors and the environment, as genetics play an important role in up to 90% of individuals with autism via over 800 currently recognized genes.Research & information: generalbicsscBiology, life sciencesbicsscGenetics (non-medical)bicsscautismASDgeneticsheterogeneitysyndromesassessmentmedicationstreatmentcausesautism spectrum disorders (ASDs)proteomicsmetabolomicsinteractomicsdisease biomarkersclinical decision support systems (CDSSs)phenotypic subgroups stratified by ASD severitysimplex familiesDNA methylationsubgroup-associated genes and biological functionsBroader Autism Phenotypegeneticautism spectrum disordermultiplex familygenetic factorsepigenetic factorsenvironmental factorspervasive developmental disorderpost-synaptic densityCNVSNPgene fusionCACNA1CCaV1.2short QT syndromedental enamel defectbioinformaticshuman geneticspharmacogenomics15q11.2 BP1-BP2 deletionBurnside-Butler syndromeclinical findingscognitionneuropsychiatric behavior developmentgenomic characterizationexome sequencingprotein–protein interaction22q13.3 duplicationauditory steady-state responseASSRSHANK3biomarkerauditory event-related potentialERPautism spectrum disordersintellectual disabilitiesResearch & information: generalBiology, life sciencesGenetics (non-medical)Butler Merlin Gedt1261076Butler Merlin GothBOOK9910566463603321Identification and Characterization of Genetic Components in Autism Spectrum Disorders 20203021929UNINA