05017nam 2201261z- 450 991055771740332120231214133128.0(CKB)5400000000046151(oapen)https://directory.doabooks.org/handle/20.500.12854/77064(EXLCZ)99540000000004615120202201d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierDedicated to the 55th Anniversary of G.B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of SciencesBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 electronic resource (234 p.)3-0365-2504-1 3-0365-2505-X The G.B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far-Eastern Branch of the Russian Academy of Sciences (PIBOC FEB RAS) was founded in 1964 in Vladivostok in the Far East of Russia. Over many years, we have been carrying out studies on the natural products of both marine and terrestrial origin. In collaboration with many Russian and foreign scientists, we have investigated many hundreds of diverse biomolecules, including steroids and terpenoids, quinoid compounds and alkaloids, polysaccharides and lipids, enzymes and lectins, proteins, and peptides. The Institute has a collection of marine microorganisms (KMM) PIBOC, which includes more than 4000 strains of marine bacteria and more than 1000 strains of marine fungi. The biological activity of natural compounds is also being studied. This book includes the 14 manuscripts which covered almost all aspects of PIBOC research activity in the fields of bioorganic chemistry, biochemistry, organic synthesis of natural compounds, marine microbiology, and genetic engineering, and we hope it will provide interesting new information for scientists working in these fields.Research & information: generalbicsscpolyhydroxylated steroidsNMR spectrastarfishAnthenoides laevigatuscytotoxicitysoft agar assaykainic aciddomoic aciddysiherbaineneodysiherbaine Amarine bacteriawhole genome sequenceporinamino acids compositionbilayer lipid membranepore-forming activityspatial structurephlorotanninsphloretholsanticancer activitycolorectal cancerradiosensitizerradiotherapy1,4-naphthoquinonesquinoid compoundsthioglycosidesquinone-sugar conjugatescytotoxic activityantibiotic activityhistochromeechinochrome Aoxidative degradationHPLC-DAD-MSNMRactinoporinsea anemoneHeteractis crispaanti-migratory activityglycosphingolipidscerebrosidesperoxidation productsstructure elucidationallylic thioetherESI-MSGC-MSmass spectraglass spongeisomalabaricanesStelletta sp.marine spongeterpenoidCobetia amphilectiCobetia litoralisCobetia pacificaCobetia marinaCobetia crustatorumidentification markersalkaline phosphatase PhoAlanosterol 14-alpha demethylaseflavonoidsenzyme inhibitionsurface plasmon resonancespectral titrationmolecular dockingZobelliagenomespolysaccharide lyase family 7alginate utilization systemparalogsorthologsrecombinant phospholipase A1Yersinia pseudotuberculosisinclusion bodiesfusion proteingreen fluorescent proteinporin gene expressionantibiotic stressphenotypic heterogeneityResearch & information: generalDmitrenok Pavel Sedt1332370Dmitrenok Pavel SothBOOK9910557717403321Dedicated to the 55th Anniversary of G.B. Elyakov Pacific Institute of Bioorganic Chemistry of the Far Eastern Branch of the Russian Academy of Sciences3040898UNINA