03573nam 2200985z- 450 991055770590332120210501(CKB)5400000000046220(oapen)https://directory.doabooks.org/handle/20.500.12854/68421(oapen)doab68421(EXLCZ)99540000000004622020202105d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierComorbidities in Chronic Kidney Disease (CKD)Basel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 online resource (184 p.)3-03936-668-8 3-03936-669-6 With a mean worldwide prevalence of 13%, chronic kidney disease imposes a massive health burden on our society. In addition to reduced kidney function, patients with chronic kidney disease increasingly suffer from cardiovascular diseases affecting the heart and vasculature. Cardiovascular diseases account for around half of the deaths of patients with advanced chronic kidney disease. However, therapeutic options are highly insufficient. The pathological mechanisms that underlie increased cardiovascular risk in patients with chronic kidney disease remain largely unknown. This Special Issue provides insights into comorbidities in CKD patients, mainly focused on increased cardiovascular risk, and summarizes current knowledge of underlying pathophysiological mechanisms.Comorbidities in Chronic Kidney Disease Medicine and Nursingbicsscageingarterial calcificationarterial stiffnessbonecalcificationcardiac fibrosiscardiorenal syndromecardiovascularcardiovascular diseasecarotid-femoral pulse wave velocitychronic kidney diseasechronodisruptionchronodisruptorcircadian rhythmCKDCKD-MBDcoagulationcomorbidityend-stage kidney diseaseendothelial dysfunctionepigeneticsexperimental rodent modelsFGF23FGFG23fibrosisgutheart failurehemodialysisinflammationinternal clockklothoKlotholeft ventricular hypertrophyleft-ventricular hypertrophylipid metabolismorgan crosstalkp-cresyl sulfateparathyroid hormonephosphatepremature ageingPTHsclerostinsecondary hyperparathyroidismsenescenceuremiauremic cardiomyopathyuremic cardiopathyuremic toxinuremic toxinsvascular calcificationWnt/β-cateninMedicine and NursingJankowski Joachimedt1332367Noels HeidiedtJankowski JoachimothNoels HeidiothBOOK9910557705903321Comorbidities in Chronic Kidney Disease (CKD)3040895UNINA