01764nam 2200337 n 450 99639177080331620221108103245.0(CKB)4940000000109063(EEBO)2248541689(UnM)99864457(EXLCZ)99494000000010906319931111d1648 uy |engurbn||||a|bb|A great victory obtained by his Excellencie the Lord Generall Fairfax[electronic resource] neer the Island of Mersey, against the forces of the Lord Goring, both by land and sea, with a list of the number that were slain and taken prisoners, the sea-men totally routed, 22 pieces of ordnance taken, with all their arms, powder, match, and bullet. Also another fight at Wivner, within two miles of Coulchester, 16. slain, 40. taken prisoners, and the surprizing of Lieut. Col. Gardner, and a party of Walloons, by capt. Fisher, with his Suffolk Horse. With their examination before the generall, and their concession, touching their marching up to the walls of London, and joyning with a party to plunder the cityLondon Printed by R.W.Anno Dom 1648[2], 6 pSigned on p.5: T. Fairfax.Annotation on Thomason copy: "June 23".Reproduction of the original in the British Library.eebo-0018Great BritainHistoryCivil War, 1642-1649CampaignsEarly works to 1800Fairfax Thomas FairfaxBaron,1612-1671.804819Cu-RivESCu-RivESCStRLINWaOLNBOOK996391770803316A great victory obtained by his Excellencie the Lord Generall Fairfax2298890UNISA05586nam 2201513z- 450 991055770560332120210501(CKB)5400000000046223(oapen)https://directory.doabooks.org/handle/20.500.12854/68639(oapen)doab68639(EXLCZ)99540000000004622320202105d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierNatural Products and NeuroprotectionBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20201 online resource (338 p.)3-03936-216-X 3-03936-217-8 Neurodegenerative diseases, including Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis, are the most common pathologies of the central nervous system currently without a cure. They share common molecular and cellular characteristics, including protein misfolding, mitochondrial dysfunction, glutamate toxicity, dysregulation of calcium homeostasis, oxidative stress, inflammation, and ageing, which contribute to neuronal death. Efforts to treat these diseases are often limited by their multifactorial etiology. Natural products, thanks to their multitarget activities, are considered promising alternatives for the treatment of neurodegeneration. This book deals with two different forms of natural products: extracts and isolated compounds. The study of the bioactivity of the extracts is extremely important as many studies have demonstrated the synergistic effect of the combination of different natural products. On the other hand, the investigation of the activity of specifically isolated natural products can be also important to understand their cellular and molecular mechanisms and to define the specific bioactive components in extracts or foods. This book can be considered an important contribution to knowledge of the neuroprotective effect of natural products and presents a great deal of information, related to both the benefits but also the limitations of their use in counteracting neurodegeneration.Biology, life sciencesbicsscResearch and information: generalbicssc5-(3,5-dihydroxyphenyl)-γ-valerolactonealgaeAlzheimer's diseaseanimal studiesantioxidantascaroside pheromoneaurapteneautophagyB-cell lymphoma 2beneficencebioactive compoundbioavailabilityblood-brain barrierC. eleganscalciumcatechincell deathCentella asiaticachaperonesChionanthus retususclinical trialcognitioncognitive dysfunctioncurcumincyclic AMPdauerdepressiondopamine neurondynamicsepigallocatechin gallateethicsflavonoidflowerfree radicalsglycogen synthase kinase 3green teaheme oxygenasehippocampusHO-1hormesishuman studiesin vitro studiesinflammationlearningLippia citriodoramedical liabilitymemorymicrobiotamitochondriamitochondrial dysfunctionmitophagyMultiple Sclerosisn/anatural compoundnatural compoundsnatural extractnatural productsneurodegenerationneurodegenerative diseaseneurodegenerative diseasesneuroinflammationneuronal signalingneuroprotectionNOnonmaleficencenutraceuticalsoxidative injuryoxidative stressParkinson's diseaseParkinson's disease (PD)patients' autonomyprotein aggregationprotein poshophatase 2proteostasisrelaxationsafety profileseaweedssexual behaviorstress responsesurvival signalssymptomsynapse losstau proteinterpenes, rotenonethymoltype 2 diabetesubiquitin-proteasomeubiquitin‒proteasome system (UPS)unfolded protein responsevascular damageVEEVitamin DVsβ-amyloid peptideBiology, life sciencesResearch and information: generalAngeloni Cristinaedt1299450Vauzour DavidedtAngeloni CristinaothVauzour DavidothBOOK9910557705603321Natural Products and Neuroprotection3025178UNINA