03733nam 2201021z- 450 991055769290332120231214133318.0(CKB)5400000000044602(oapen)https://directory.doabooks.org/handle/20.500.12854/68354(EXLCZ)99540000000004460220202105d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierAdvances in Diagnosis and Therapy of Neuroendocrine NeoplasmsBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 electronic resource (144 p.)3-03943-745-3 3-03943-746-1 This Special Issue is dedicated to neuroendocrine neoplasms (NENs), a category of malignancy that demonstrates wide clinical heterogeneity, posing major challenges in diagnosis and management. There have been significant advances in the field of NEN genomics, pathology, imaging, and treatment over the past five years. NENs are examples of rare tumours (although their incidence and prevalence are increasing) where international collaborative efforts have allowed the generation of high-level evidence to guide optimal patient-centred care. This issue presents both reviews and original papers to provide comprehensive state-of-the-art understanding of this fascinating disease.Medicinebicsscsmall bowel neuroendocrine tumourspancreatic neuroendocrine tumoursliver metastasesmidgutmeta-analysisneuroendocrine tumorscarcinoid heart diseasecarcinoid syndromesomatostatin analoguesmetastasesmultidisciplinarymanagementoutcomegradingstagingneuroendocrine neoplasmschemotherapytemozolomidemetronomic treatmentsecond-lineNOTCHcancer-driven genesmutational mechanismgermline mutationssmall cell lung carcinomapancreatic NETsmall bowel NETmedullary thyroid carcinomamalignant castration-resistant prostatic cellsquality performance indicatorsQPIscancer careneuroendocrine tumourNETsmodified DelphiCommNETspancreatic neuroendocrine neoplasmsneuroendocrine tumorlong-term functional outcomespancreatectomydiabetes mellituspancreatic exocrine insufficiencybody mass indexparenchyma-sparing surgeryneuroendocrine tumourscurative surgeryresectionfollow-upguidelinesrelapserecurrencerisk factormixed non-neuroendocrine neuroendocrine neoplasmsMiNENsmixed adeno-neuroendocrine carcinomaMANEC2017 WHO classification2019 WHO classificationMedicineSegelov Evaedt1311964Segelov EvaothBOOK9910557692903321Advances in Diagnosis and Therapy of Neuroendocrine Neoplasms3030628UNINA