03774nam 2201033z- 450 991055769290332120210501(CKB)5400000000044602(oapen)https://directory.doabooks.org/handle/20.500.12854/68354(oapen)doab68354(EXLCZ)99540000000004460220202105d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierAdvances in Diagnosis and Therapy of Neuroendocrine NeoplasmsBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 online resource (144 p.)3-03943-745-3 3-03943-746-1 This Special Issue is dedicated to neuroendocrine neoplasms (NENs), a category of malignancy that demonstrates wide clinical heterogeneity, posing major challenges in diagnosis and management. There have been significant advances in the field of NEN genomics, pathology, imaging, and treatment over the past five years. NENs are examples of rare tumours (although their incidence and prevalence are increasing) where international collaborative efforts have allowed the generation of high-level evidence to guide optimal patient-centred care. This issue presents both reviews and original papers to provide comprehensive state-of-the-art understanding of this fascinating disease.Medicine and Nursingbicssc2017 WHO classification2019 WHO classificationbody mass indexcancer carecancer-driven genescarcinoid heart diseasecarcinoid syndromechemotherapyCommNETscurative surgerydiabetes mellitusfollow-upgermline mutationsgradingguidelinesliver metastaseslong-term functional outcomesmalignant castration-resistant prostatic cellsmanagementMANECmedullary thyroid carcinomameta-analysismetastasesmetronomic treatmentmidgutMiNENsmixed adeno-neuroendocrine carcinomamixed non-neuroendocrine neuroendocrine neoplasmsmodified Delphimultidisciplinarymutational mechanismNETsneuroendocrine neoplasmsneuroendocrine tumorneuroendocrine tumorsneuroendocrine tumourneuroendocrine tumoursNOTCHoutcomepancreatectomypancreatic exocrine insufficiencypancreatic NETpancreatic neuroendocrine neoplasmspancreatic neuroendocrine tumoursparenchyma-sparing surgeryQPIsquality performance indicatorsrecurrencerelapseresectionrisk factorsecond-linesmall bowel NETsmall bowel neuroendocrine tumourssmall cell lung carcinomasomatostatin analoguesstagingtemozolomideMedicine and NursingSegelov Evaedt1311964Segelov EvaothBOOK9910557692903321Advances in Diagnosis and Therapy of Neuroendocrine Neoplasms3030628UNINA