03201nam 2200841z- 450 991055768440332120231214132834.0(CKB)5400000000044688(oapen)https://directory.doabooks.org/handle/20.500.12854/77052(EXLCZ)99540000000004468820202201d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierMarine Carotenoids in Inflammation and CancerBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 electronic resource (234 p.)3-0365-2516-5 3-0365-2517-3 This Special Issue covers both the in vitro and in vivo evaluation of marine carotenoids with anti-inflammatory and anticancer activities as well as clinical trials conducted in humans. Among the properties of carotenoids discussed in this book, it is worth highlighting the potential of astaxanthin and its precursor metabolite, adonixanthin, since oral administration of these carotenoids has shown beneficial effects on glioblastoma for the first time by suppressing cell proliferation and migration. In addition, astaxanthin has been shown to inhibit Helicobacter pylori-induced gastric carcinoma cell motility and, consequently, cancer progression through the inhibition of cytoskeleton reorganization. In addition, a carotenoid-containing lipid extract of Gloeothece sp. has demonstrated antioxidant, anti-inflammatory, and anticancer properties in vitro.MedicinebicsscHelicobacter pylorigastric carcinomaastaxanthincell motilitycell migrationbioavailabilitycarotenoidsmarinenanoformulationoxidative stressreactive oxygen speciesbraincanceroral administrationparacoccsu carotinifaciensxanthophyll carotenoidphotodamageskin cancerphotoagingmarine carotenoidsfucoxanthinxanthophyllsnatural compoundsalgaebioactivehealthneuroprotective agentneuroinflammationneurological diseasesmicroalgaeinflammationbreast cancerbacterioruberinantioxidantpro-oxidantluteinβ-carotenelinolenic acidlinoleic acidlipidic compoundsPUFAsMedicineTalero Elenaedt1293407Ávila-Román JavieredtTalero ElenaothÁvila-Román JavierothBOOK9910557684403321Marine Carotenoids in Inflammation and Cancer3028861UNINA