04776nam 2201093z- 450 991055768170332120231214133043.0(CKB)5400000000044715(oapen)https://directory.doabooks.org/handle/20.500.12854/76922(EXLCZ)99540000000004471520202201d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierMarine Carbohydrate-Based Compounds with Medicinal PropertiesBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 electronic resource (214 p.)3-0365-2091-0 3-0365-2092-9 The marine environment is considered one of the most important sources of natural bioactive compounds with extremely rich biodiversity. Marine glycans are remarkable molecules, playing a determinant role in biological processes. Marine сarbohydrate-containing substances have drawn increasing attention in the field of biomedicine for their various biological activities, such as antitumor, antivirus, hypoglycemic, immunomodulatory, and anticoagulant. These compounds obtained from marine sources, such as algae, microbes, and animals, are usually biodegradable and biocompatible, and exhibit biological properties that contribute to the discovery of a wide range of new bioactive substances with special pharmacological properties of interest to medicine. Carbohydrate-based compounds include glycans, glycoproteins, proteoglycans, glycolipids, and low-molecular and complex glycosides of differential origin. Many of the polysaccharides allow for loading lower drug dosages, which may lead to a drastic reduction of the side effects caused by the drugs. In addition, the structure of polysaccharides can be relatively easily modified in order to synthesize derivatives with desirable characteristics for drug delivery. Complexes on the basis of carbohydrates are often prepared to improve their functional properties. In this Special Issue, we seek to contribute to the discussion of various aspects of marine carbohydrate-containing compounds and provide a unique platform for a new concept for their use in medicine in order to continue to facilitate further research in this area.Medicinebicsscchitosan-gentamicin conjugateantimicrobialanti-inflammatoryscald repairsulfated polysaccharidesgalactansgreen seaweedNMRimmunostimulationinflammatory mediatorscarrageenanlipopolysaccharidemacromolecular structurenonspecific resistance to lipopolysaccharidecytokinesenteric infectionssalmonellosisglyceroglycolipid metabolismphosphate starvationtranscriptomeglyceroglycolipid homeostasischitosanpolyelectrolyte complexcytokinenitric oxideanti-inflammatory activityUlva pertusapolysaccharidescolitisantioxidantexopolysaccharidestructureVibrio alginolyticusEpidermistchitosan oligosaccharidesinflammation cytokinesintestineoxidative statusoxidative stressPorphyridium marinumhigh pressure homogenizerantibacterial activityanti-biofilm activityanti-cancer activityalginate lyasecold-adaptedexo/endo-typeAlteromonas portusoligosaccharideantioxidant activityexopolysaccharidesscandiumtheranosticcancer cell linesproliferationlaminarinfucoidangastrointestinal tractmicrobiomeswinepost-weaningantibiotic alternativesMedicineYermak Irina Medt1303785Davydova ViktoriaedtYermak Irina MothDavydova ViktoriaothBOOK9910557681703321Marine Carbohydrate-Based Compounds with Medicinal Properties3027217UNINA