08937nam 2202677z- 450 991055763170332120210501(CKB)5400000000045097(oapen)https://directory.doabooks.org/handle/20.500.12854/68656(oapen)doab68656(EXLCZ)99540000000004509720202105d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierPeptides for Health Benefits 2019Volume 1Basel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20201 online resource (340 p.)3-03936-080-9 3-03936-081-7 In recent years, peptides have received increased interest from the pharmaceutical industry. The high potency, specificity, and safety profile are the main strengths of bioactive peptides as new and promising therapies that may fill the gap between small molecules and protein drugs. These positive attributes have renewed interest in the discovery, optimization, and development of peptides as pharmacological therapy. Among bioactive peptides, those released from food sources have acquired importance as nutraceutical and active components in functional foods because they possess regulatory functions that can lead to health benefits. This Special Issue covers a selection of recent research papers and reviews in the field of bioactive peptides. It covers all aspects of peptide research in relation to health promotion. In particular, it emphasizes current knowledge and research trends concerning bioactive peptides, including identification and quantification of peptides from new sources, methods for their production and purification, structure-function relationships, mechanisms of action, in vitro and in vivo assays for the evaluation of their bioactivity, physiological evidence to support health benefits, and peptide stability and bioavailability. Papers regarding the development of new drugs, functional foods, or nutraceuticals based on bioactive peptides were also considered.Peptides for Health Benefits 2019 Biology, life sciencesbicsscResearch & information: generalbicsscACE-inhibitory activityacrylamideairway inflammationalcalase hydrolysateAlzheimer's diseaseAMDAMP identification and designamyloidamyloid fibrilsand endothelial regenerationangiogenic precursor cellsangiotensin I converting enzymeanti-biofilm peptidesanti-inflammatoryantibiotic resistanceantifungal activityantigen-specificantihypertensive peptidesantimicrobial peptideantimicrobial peptidesantimicrobial peptides (AMPs)antimicrobial resistanceantioxidant activityantioxidant peptideantiproliferative assayantisepsis, peptide antibioticsapolipoprotein EarthritisasthmaAβ peptidebioactive peptidebioactive peptidesbiomarkersBIOPEP-UWM databasebiosynthesisbone erosioncancer antigencancer stem cellscartilage destructioncathelicidinsCec-analogsCecropinscentral nervous system diseaseschemopreventionChlorella sorokinianachronic diseasesClostridioides difficileCNVcollagencollagen peptidecolorectal cancercombinatorial libraryconfocal microscopyconjugationcopperCrassostrea angulatacryptidesCXCR3cystic fibrosiscytoprotective effectdatabasedefensinsdiseasesdocetaxeldoxorubicindry-cured pork hamdyslipidemiaendothelial dysfunctionendothelial progenitor cellsenergy expenditureenteric nervous systemenzymeextra domain Bfermentationfetal bovine serum (FBS)fibroblastsfibronectinFmoc/tBufood intake regulationfood-derivedfoodsformyl peptide receptorsFPYLRHfresh tissuefunctional foodgalaningender differencesgliomaGPR10Histatin-5host defense peptidesHs02human antimicrobial peptideshuman keratinocyteshumanized mousehybrid peptidehydrolysishydroxyprolyl-glycine (Hyp-Gly)hyperglycemiahypertensionimmune checkpoint inhibitorimmune responseimmune suppressionimmunomodulantin silicoIn situ tetramer staininginflammationinflammatory bowel diseaseinsectsintragenic antimicrobial peptideLactoferricin B (Lfcin B)library designligandslunasinMDAMDR infectious diseasesmembrane activityMHC tetramermigrationmiiuy croaker (Miichthys miiuy)mode of actionmolecular blind dockingmolecular dockingmolecular weightmonocyteMRSAmultimeric peptidesmutagenesisn/anano liquid chromatography tandem mass spectrometry (nanoLC-nanoESI MS/MS)neuroprotectionneurotensinNF-κBnon-atopic asthmanutraceuticalsnutritionobesityoral deliveryosteostatinoxidative stresspegylated glucagon-like peptide 1peptidepeptide vaccinepeptide-drug conjugatephysico-chemical propertiesPI3K/Akt pathwaypidotimodpigpiscidinsplateletspolymicrobial biofilmspro-inflammatorypro-inflammatory cytokinesprolactin-releasing peptideprolyl-hydroxyproline (Pro-Hyp)prostate cancerprotection abilityproteolysisproteome microarrayproteomicspseudin-2Pseudomonas aeruginosapulmonary emphysemaRF-amide peptidesrheumatic diseasesscreeningsheepskinsignalingSjögren's syndromeSMILES codesolid-phase synthesissPLA2Staphylococcus aureusstomachswim bladdersynergistic effectssynergyT cellT cellstargetingtemporintherapeutic potentialtype 1 diabetesvasoactive intestinal peptideVEGFR1velvet antlerVPAC1 receptorVPAC2 receptorwhey peptidesΑβ oligomerBiology, life sciencesResearch & information: generalHernández-Ledesma Blancaedt906315Martínez-Villaluenga CristinaedtHernández-Ledesma BlancaothMartínez-Villaluenga CristinaothBOOK9910557631703321Peptides for Health Benefits 20193013216UNINA