03130nam 2200733z- 450 991055761510332120231214133413.0(CKB)5400000000045251(oapen)https://directory.doabooks.org/handle/20.500.12854/79602(EXLCZ)99540000000004525120202203d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierMonoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.0BaselMDPI - Multidisciplinary Digital Publishing Institute20221 electronic resource (112 p.)3-0365-3165-3 3-0365-3164-5 Monoclonal antibodies (mAbs) are among the most specialised molecules for the recognition and capture of specific analytes. Hundreds of thousands of mAbs have been generated for a large number of different antigens with increasing affinity and specificity and are available for the most diverse purposes. Many of them have been validated as irreplaceable agents for diagnosis and therapy or as unique reagents for research. Others have been developed using emerging technologies that avoid the need for animal immunisation. This short book strives to gather the perspective view of the various contributing authors and to survey the new strategic assets adopted to generate novel monoclonal antibodies or surrogates, such as Fab, Fab2, ScFv and nanobodies, which have an increasing impact in biomedicine as therapeutic or diagnostic assets in various diseases.Research & information: generalbicsscBiology, life sciencesbicsscPRAMEmAbbio-layer interferometryepitope identificationmonoclonal antibodyfree radicalprotein aggregationoxidationexcipientfoot-and-mouth disease virustype Otype Aphage displayantibodycompetitive ELISAatherosclerosisnano-emulsionmagnetic resonance imagingstealthhuman antibodyC. auriscandidiasismultidrug resistancemonoclonal antibodiesuniversal antibodiescell wallpassive immunizationcell-based panningsemi-automated cell panningFGFR3-specific antibodyResearch & information: generalBiology, life sciencesRuvo Menottiedt1292387Sandomenico AnnamariaedtRuvo MenottiothSandomenico AnnamariaothBOOK9910557615103321Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy 2.03022242UNINA