04123nam 2201057z- 450 991055761190332120220321(CKB)5400000000045283(oapen)https://directory.doabooks.org/handle/20.500.12854/79660(oapen)doab79660(EXLCZ)99540000000004528320202203d2022 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierNatural Product Genomics and Metabolomics of Marine BacteriaBaselMDPI - Multidisciplinary Digital Publishing Institute20221 online resource (244 p.)3-0365-3299-4 3-0365-3300-1 Marine organisms are a treasure trove for the discovery of novel natural products, and, thus, marine natural products have been a focus of interest for researchers for decades. Some marine bacteria are prolific producers of natural products, occurring either free-living or, as recently shown, in symbiosis with marine animals. Recent advances in DNA sequencing have led to an enormous increase in published bacterial genomes and bioinformatics tools to analyze natural product biosynthetic potential by various "genome mining" approaches. Similarly, analytical NMR and MS methods for the characterization and comparison of metabolomes of natural product producers have advanced. Novel interdisciplinary approaches combine genomics and metabolomics data for accelerated and targeted natural product discovery. This Special Issue invites articles from both genomics- and metabolomics-driven studies on marine bacteria with a focus on natural product discovery and characterization. We particularly welcome articles that combine genomics and metabolomic approaches for the dereplication and characterization of marine bacterial natural products.MedicinebicsscActinobacteriaantibioticantibioticsanticancerbacterial natural productsbacteriocinsbioactivitybiodiversitybiosynthetic gene clusterschemogeographychitinchitin degradation machinerychitinasecomparative genomicsCuSO4·5H2O assistedcyanobacteriacyclodepsipeptidesdereplicationdifferential gDNA isolationdrug discoverydrug screeningenterococcifilamentous bacteriagene cluster networkinggenome mininggenome-wide analysisgenomic comparisongenomicsGNPSHCVIndonesiakeratinaseskeratinolytic proteasesmarinemarine Actinobacteriamarine natural productsmarine spongesmarine-derived Streptomycesmass spectrometrymetabolomicsmicrococcin P1 and P2Moorea producensMoorena bouilloniinatural productsNeolyngbyanovel antibioticspaired omicsplant pathogenPolarprobioticsPseudoalteromonassea cucumbersecondary metabolitesSouth China Seaspecialised metabolitesstalked diatomsStreptomyces spp.symbiontswenchangamidewild marine speciesMedicineCrüsemann Maxedt1328687Crüsemann MaxothBOOK9910557611903321Natural Product Genomics and Metabolomics of Marine Bacteria3038825UNINA