03089nam 2200757z- 450 991055760260332120231214133133.0(CKB)5400000000045377(oapen)https://directory.doabooks.org/handle/20.500.12854/69310(EXLCZ)99540000000004537720202105d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierHost-Directed Therapies for TuberculosisBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20201 electronic resource (120 p.)3-03943-501-9 3-03943-502-7 TB is considered as one of the oldest documented infectious diseases in the world and is believed to be the leading cause of mortality due to a single infectious agent. Mtb, the causative agent responsible for TB, continues to afflict millions of people worldwide. Furthermore, one-third of the entire world's population has latent TB. Consequently, there has been a worldwide effort to eradicate and limit the spread of Mtb through the use of antibiotics. However, management of TB is becoming more challenging with the emergence of drug-resistant and multi-drug resistant strains of Mtb. Furthermore, when administered, many of the anti-TB drugs commonly present severe complications and side effects. Novel approaches to enhance the host immune responses to completely eradicate Mtb infection are urgently needed. This Special Issue will therefore cover most recent advances in the area of host-directed therapies for TB.Research & information: generalbicsscBiology, life sciencesbicsscMycobacterium tuberculosishost-directed therapiesimmune responsestuberculosislung cancermisdiagnosisinvasive procedurerevisingantiplateletaspirinimmunomodulationsurvivalTaiwanlatent infectionpulmonaryrabbitiron supplementationpathologyimmune responsegene expressionPerls’ stainautophagyM. tbBCG vaccinationimmune exhaustionglutathionecytokinesgranulomastype 2 diabetesco-morbiditiesco-infectionsinflammationredox imbalanceantioxidantsResearch & information: generalBiology, life sciencesVenketaraman Vishwanathedt1303388Venketaraman VishwanathothBOOK9910557602603321Host-Directed Therapies for Tuberculosis3026986UNINA