03094nam 2200937z- 450 991055757840332120231214133329.0(CKB)5400000000043865(oapen)https://directory.doabooks.org/handle/20.500.12854/76974(EXLCZ)99540000000004386520202201d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierHost Immune Responses and Pathogenesis to Brucella spp. InfectionBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 electronic resource (162 p.)3-0365-2418-5 3-0365-2419-3 Brucellosis, caused by the facultative intracellular bacteria Brucella species, is one the most prevalent zoonosis worldwide. • The articles described in this book report several aspects of host-Brucella interactions. • The findings described here will help to advance in the comprehension of bacterial pathogenesis and contribute to the future development of drugs or vaccines to control brucellosis.Research & information: generalbicsscRecombinant vaccinedivalent vaccinebrucellosisOmp25L7/L12Brucella abortus 544ST2 receptorBrucella abortusoral infectionhuman endometrial cellsinternalizationintracellular replicationdecidualizationchemokinesmacrophagesBrucellaHSCMHCIL-10cell cycle(p)ppGpprshneurobrucellosisplateletsbrain microvascular endothelial cellsendothelial cellsadhesinsIg-like domainmonomeric autotransporterstrimeric autotransportersextracellular matrixpolar localizationvirulence factorsvaccine candidatesfibronectincanonical inflammasomenon-canonical inflammasomeNLRpyroptosisASCcaspase-11caspase-1IL-1βgDNAreplication nichereservoirpersistencesurvivalchronic infectionResearch & information: generalOliveira Sergio Costaedt1302758Giambartolomei GuillermoedtOliveira Sergio CostaothGiambartolomei GuillermoothBOOK9910557578403321Host Immune Responses and Pathogenesis to Brucella spp. Infection3026521UNINA