03464nam 2201093z- 450 991055757390332120231214133142.0(CKB)5400000000043910(oapen)https://directory.doabooks.org/handle/20.500.12854/69144(EXLCZ)99540000000004391020202105d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierMarine Bioactive Natural Product Studies—A Southern Hemisphere PerspectiveBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20201 electronic resource (142 p.)3-03943-188-9 3-03943-189-7 The search for bioactive secondary metabolites from marine organisms has been an active area of research since the 1950s. The distinct biodiversity of the marine environment has afforded a vast array of unique secondary metabolites, many of which possess potent biological activities. This Special Issue of Marine Drugs will highlight recent bioactive marine natural product studies conducted by southern hemisphere scientists on an array of marine organisms.MedicinebicsscSinulariaAlcyoniidaeanticancer activitylobanecembranediterpeneconotoxinsShK toxinion channelsdockingmolecular dynamicspotential of mean forcefree energy perturbationbioactivitybiosynthesisbrominated secondary metabolitescholine esterindolesea cucumberviscerasaponinsmass spectrometryMALDIESIHPCPCtriterpene glycosidesstructure elucidationbioactive compoundsmarine invertebrateEchinodermataholothurianCnemidocarpa stoloniferataurine amidePC3 cell lineimmunofluorescence assaythiaplidiaquinoneAplidiumascidianthiazinoquinoneapoptosisJurkatcytotoxicitymalariafarnesyltransferasesynthesisthiaplakortoneregioisomertricyclicnatural product scaffoldX-raycrystalPlasmodium falciparumantiplasmodialcephalostatinmandelalidemethicillin resistant Staphylococcus aureusMRSA PKbisindole alkaloidssalternamide A (SA)HIF-1αPI3K/Akt/mTORp42/p44 MAPKSTAT3cell deathMedicineUrban Sylviaedt1290022Urban SylviaothBOOK9910557573903321Marine Bioactive Natural Product Studies—A Southern Hemisphere Perspective3021311UNINA