03482nam 2200973z- 450 991055755230332120210501(CKB)5400000000044083(oapen)https://directory.doabooks.org/handle/20.500.12854/68386(oapen)doab68386(EXLCZ)99540000000004408320202105d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierCocrystal Applications in Drug DeliveryBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 online resource (172 p.)3-03943-983-9 3-03943-984-7 In 2015, the first pharmaceutical cocrystal was approved by the FDA. Since then, the number of cocrystals on the market and in the development pipeline has been slowly but steadily growing. It is now well established that cocrystals are a versatile new approach to oral drug formulation. This Reprint Book is a collection of articles that show the utility of pharmaceutical cocrystals and various aspects of cocrystal research: • Cocrystals as a strategy to modify the physicochemical properties of a drug such as dissolution behaviour, tabletability, and melting point; • Development of new coformers; • Screening studies for multiple cocrystal forms; • Cocrystals in nano-sized drug delivery.Research & information: generalbicsscbarbituric acidcocrystalcocrystalscompactioncrystal engineeringcrystal structurecrystallization inhibitorsdesign of experimentsdiclofenac sodiumdissolutiondissolution behaviordissolution ratedrug-polymer interactionsformulationHIV/AIDSimidazole N-oxidesinterparticulate bonding areainterparticulate bonding strengthitraconazoleL-prolinelamivudinemechanochemistrymonohydratemulticomponent crystalmulticomponent crystalsn/anano co-crystalsnanoindentationnefiracetamnitazoxanideparticle sizepharmaceutical cocrystalspolydispersity indexQuality by Designsalt cocrystalslip planesolid statesolid state NMRsolid-statesolubilitysonochemistrystabilitysupersaturated formulationssurface topologytabletabilityterephthalic acidtetrahydratethermal analysisthiobarbituric acidwettabilityX-ray Diffractionzeta potentialzidovudineResearch & information: generalErxleben Andreaedt1290197Erxleben AndreaothBOOK9910557552303321Cocrystal Applications in Drug Delivery3021414UNINA