04832nam 2201333z- 450 991055755160332120231214133510.0(CKB)5400000000044090(oapen)https://directory.doabooks.org/handle/20.500.12854/69088(EXLCZ)99540000000004409020202105d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierMembrane–Peptide InteractionsFrom Basics to Current ApplicationsBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20201 electronic resource (302 p.)3-03943-022-X 3-03943-023-8 This book summarizes the importance of peptide–membrane interactions, mostly aiming at developing new therapeutic approaches. The experimental and computational methodologies used to investigate such interactions reveal the evolution of existing biophysical methodologies, shedding some light on potential applications of peptides, as well as on the improvement of their design. Understanding the determinants for peptide–membrane interactions may also improve the knowledge of membrane functions such as the membrane transport, fusion, and signaling processes, contributing to the development of new agents for highly relevant applications ranging from disease treatment to food technology.Membrane–Peptide Interactions Membrane–Peptide Interactions Research & information: generalbicsscBiology, life sciencesbicssctachyplesinhost defense peptideanticancerantimicrobialantibiofilmpeptide-membrane interactionstructure-activitymodel membranesnuclear magnetic resonance solution structureaccelerated molecular dynamicsalamethicinmembranepeptaibolcell-penetrating peptidepeptide–lipid interactionlipid model systemsmolecular dynamicsNMRmembrane biophysicsantimicrobial peptidesnon-lytic peptidesbacterial membranescalcium hydroxidechemokinehuman beta defensin-3-C15human dental pulp cellStreptococcus gordonii lipoproteinluffa spongephosphopeptidemass spectrometryMatrix-assisted laser desorption ionizationsolid-phase extractionsurface plasmon resonancemelittinliposomespeptide–lipid interactionsanti-microbial peptidespore-forming peptidesESKAPE pathogensStaphylococcus aureusKR12LL-37lipopeptidecritical aggregation concentrationCD spectroscopybiofilmcytotoxicityorganismssequence analysismachine learningfeature selectionsesame proteinACE inhibitory peptidessimulated gastrointestinal digestionamino acid sequencemolecular dockingchionodracinescircular dichroismmembrane affinitycell-penetrating peptidescircular dichroism spectroscopyatomic force microscopymycolic acidLangmuir monolayerdrug–peptide conjugatesmetastasis model of B16F10 melanomaPisum sativum defensin 1 (Psd1)anti-metastatic activityglucosylceramide (GlcCer)cyclin Fanti-inflammatory peptidecell permeable peptideheparin-binding peptidecollagen-induced arthritisinducible nitric oxideinterferon gammainterleukin-6EnbrelResearch & information: generalBiology, life sciencesSantos Nuno Cedt900048Gonçalves SóniaedtSantos Nuno CothGonçalves SóniaothBOOK9910557551603321Membrane–Peptide Interactions3021985UNINA