02769nam 22005053a 450 991055746050332120250203235434.09783038975717303897571010.3390/books978-3-03897-571-7(CKB)4100000010106508(oapen)https://directory.doabooks.org/handle/20.500.12854/47256(ScCtBLL)4192f3f3-12cd-48d7-86fd-709f95c89ffe(OCoLC)1163844667(oapen)doab47256(EXLCZ)99410000001010650820250203i20192019 uu engurmn|---annantxtrdacontentcrdamediacrrdacarrierExtracellular Matrix in Development and DiseaseJulia OxfordMDPI - Multidisciplinary Digital Publishing Institute2019Basel, Switzerland :MDPI,2019.1 electronic resource (356 p.)9783038975700 3038975702 The extracellular matrix in development and disease deals with the molecular and cellular aspects of development and disease. Cells exist in three-dimensional scaffolding called the extracellular matrix. The matrix holds together the millions of cells that make up our blood vessels, organs, skin, and all tissues of the body. The matrix serves as a reservoir of signaling molecules as well. In bacterial cultures, biofilms form as an extracellular matrix and play essential roles in disease and drug resistance. Topics such as matrix structure and function, cell attachment and cell surface proteins mediating cell-matrix interactions, synthesis, regulation, composition, structure, assembly, remodeling, and function of the matrix are included. A common thread uniting the topics is the essential nature that the matrix plays in normal development and pathophysiology. Providing new knowledge will lead us to improved diagnostics, the preventions of disease progression, and therapeutic strategies for the repair and regeneration of tissues. Topics such as the extracellular matrix in hereditary diseases, reproduction, cancer, muscle, and tissue engineering applications, and diverse roles for integrins, are included in this collection.Biology, life sciencesbicssctissue engineeringembryonic developmentbiofilmcollagenfibrosisextracellular matrixdegenerative diseaseBiology, life sciencesOxford Julia1787742ScCtBLLScCtBLLBOOK9910557460503321Extracellular Matrix in Development and Disease4321376UNINA