02283nam 2200505z- 450 991055743420332120211118(CKB)5400000000043381(oapen)https://directory.doabooks.org/handle/20.500.12854/73858(oapen)doab73858(EXLCZ)99540000000004338120202111d2020 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierOmics and Systems Approaches to Study the Biology and Applications of Lactic Acid BacteriaFrontiers Media SA20201 online resource (309 p.)2-88963-717-4 This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contactMedical microbiology & virologybicsscMicrobiology (non-medical)bicsscScience: general issuesbicsscfermentationLactic acid bacteriapathogenprobioticstarterMedical microbiology & virologyMicrobiology (non-medical)Science: general issuesPapadimitriou Konstantinosedt1314855Kok JanedtRenault PierreedtKline KimberlyedtPapadimitriou KonstantinosothKok JanothRenault PierreothKline KimberlyothBOOK9910557434203321Omics and Systems Approaches to Study the Biology and Applications of Lactic Acid Bacteria3032052UNINA04125nam 22007695 450 991072839690332120251008144934.09783031295416(electronic bk.)978303129540910.1007/978-3-031-29541-6(MiAaPQ)EBC30552979(Au-PeEL)EBL30552979(OCoLC)1380875404(DE-He213)978-3-031-29541-6(BIP)089067678(PPN)270616381(CKB)26784778600041(EXLCZ)992678477860004120230526d2023 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierAdvances in Pharmacokinetics and Pharmacodynamics /edited by Panos Macheras1st ed. 2023.Cham :Springer International Publishing :Imprint: Springer,2023.1 online resource (208 pages)AAPS Introductions in the Pharmaceutical Sciences,2522-8358 ;9Print version: Macheras, Panos Advances in Pharmacokinetics and Pharmacodynamics Cham : Springer International Publishing AG,c2023 9783031295409 Pharmacokinetics -- Chapter 1: Current status in PBPK modeling -- Chapter 2: Physiologically based biopharmaceutics modeling (PBBM) Application on Food Effect Assessment -- Chapter 3: Physiologically based finite time pharmacokinetic (PBFTPK) models: Inception and development -- Chapter 4: Physiologically based finite time pharmacokinetic (PBFTPK) models: Applications -- Pharmacodynamics -- Chapter 5: Pharmacokinetic – Pharmacodynamic Modelling and Simulation in Clinical Practice and Studies -- Chapter 6: On the Verge of Impossibility: Accounting for Variability Arising from Permutations of Comorbidities that Affect the Fate of Drugs in the Human Body -- Chapter 7: Impact of Clinical Pharmacology on the Modernization of Drug Development and Regulation.This book provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). The pharmacokinetics section covers the state of the art in Physiologically Based Pharmacokinetic (PBPK) modeling (Chapter 1) as well as the assessment of food effect on drug absorption using PBPK modeling (Chapter 2). Chapters 3 and 4 describe the recent development of Physiologically Based Finite Time Pharmacokinetic (PBFTPK) models and their applications to pharmacokinetic data. The pharmacodynamics section focuses on PK/PD modeling. Chapter 5 provides an overview of PK/PD modeling and simulation in clinical practice and studies. Chapter 6 deals with the subject/physiology variability issue encountered in PK/PD studies, while Chapter 7 reviews the influence of clinical pharmacology in the modernization of drug development and regulation. This book is an essential reference for pharmaceutical scientists.AAPS Introductions in the Pharmaceutical Sciences,2522-8358 ;9Drug delivery systemsDrugsDesignPharmaceutical chemistryMetabolismPharmacologyClinical biochemistryDrug DeliveryStructure-Based Drug DesignPharmaceuticsMetabolismPharmacologyMedical BiochemistryDrug delivery systems.DrugsDesign.Pharmaceutical chemistry.Metabolism.Pharmacology.Clinical biochemistry.Drug Delivery.Structure-Based Drug Design.Pharmaceutics.Metabolism.Pharmacology.Medical Biochemistry.615.7615.7Macheras Panos755977Macheras PanosothMiAaPQMiAaPQMiAaPQ9910728396903321Advances in Pharmacokinetics and Pharmacodynamics3379512UNINA