03989oam 2200673I 450 991055742460332120190503073416.00-262-31460-6(CKB)2550000001163178(EBL)3339710(SSID)ssj0001062521(PQKBManifestationID)11675612(PQKBTitleCode)TC0001062521(PQKBWorkID)11017329(PQKB)10937775(StDuBDS)EDZ0000234245(MiAaPQ)EBC3339710(OCoLC)863672798(OCoLC)868916158(OCoLC)881734135(OCoLC)990660707(OCoLC-P)863672798(MaCbMITP)9876(oapen)https://directory.doabooks.org/handle/20.500.12854/78519(EXLCZ)99255000000116317820131122d2013 uy 0engur|n|---|||||txtccrSchizophrenia evolution and synthesis /edited by Steven M. Silverstein, Bita Moghaddam, and Til Wykes ; program advisory committee, Anil K. Malhotra, John McGrath, Andreas Meyer-Lindenberg, Bita Moghaddam, Steven M. Silverstein, Til WykesCambridge, Massachusetts ;London, England :The MIT Press,[2013]©20131 online resource (403 p.)Strüngmann Forum reportsDescription based upon print version of record.0-262-01962-0 1-306-14065-X Includes bibliographies and index.Contents; The Ernst Strüngmann Forum; List of Contributors; 1 Schizophrenia; Heterogeneity; 2 What Kind of a Thing Is Schizophrenia?; 3 How the Diagnosis of Schizophrenia Impeded the Advance of Knowledge (and What to Do About It); 4 What Dimensions of Heterogeneity Are Relevant for Treatment Outcome?; 5 Which Aspects of Heterogeneity Are Useful to Translational Success?; Risk and Resilience; 6 How Should Resilience Factors Be Incorporated in Treatment Development?; 7 Insights into New Treatments for Early Psychosis from Genetic, Neurodevelopment,and Cognitive Neuroscience Research8 From Epidemiology to Mechanisms of Illness9 How Can Risk and Resilience Factors Be Leveraged to Optimize Discovery Pathways?; Models; 10 Human Cell Models for Schizophrenia; 11 How Can Animal Models Be Better Utilized?; 12 How Can Computational Models Be Better Utilized for Understanding and Treating Schizophrenia?; 13 How Can Models Be Better Utilized to Enhance Outcome?; Development and Treatment; 14 Why Kraepelin Was Right; 15 What Will the Next Generation of Psychosocial Treatments Look Like?; 16 Creative Solutions to Overcoming Barriers in Treatment Utilization17 What Is Necessary to Enhance Development and Utilization of Treatment?Bibliography; Subject IndexDespite major advances in methodology and thousands of published studies every year, treatment outcomes in schizophrenia have not improved over the last 50 years. Moreover, we still lack strategies for prevention and we do not yet understand how the interaction of genetic, developmental, and environmental factors contribute to the disorder. In this book, leading researchers consider conceptual and technical obstacles to progress in understanding schizophrenia and suggest novel strategies for advancing research and treatment.Strüngmann Forum ReportsSchizophreniaSchizophreniaEtiologyClinical medicineDecision makingNEUROSCIENCE/GeneralSchizophrenia.SchizophreniaEtiology.Clinical medicineDecision making.616.89/8Silverstein Steven M.Moghaddam BitaWykes TilOCoLC-POCoLC-PBOOK9910557424603321Schizophrenia1411695UNINA