00820nam--2200313---450 99000129903020331620201204093247.0000129903USA01000129903(ALEPH)000129903USA0100012990320031203d1947----km-y0itay0103----baitaIT||||||||001yy<<La>> Controriforma in ItaliaMassimo PetrocchiRomaAVIO1947284 p.22 cm20012001001-------2001PETROCCHI,Massimo<1918-1991>68357ITsalbcISBD990001299030203316X.2.B. 492(III-D-95)3121 L.M.III-DBKUMAControriforma in Italia502424UNISA01680nam 2200325Ia 450 99639431780331620221107143741.0(CKB)3450000000091842(EEBO)2240877006(OCoLC)11861898(EXLCZ)99345000000009184219850329d1674 uy |engurbn||||a|bb|The goldsmiths' jubile, or, Londons triumphs[electronic resource] containing, a description of the several pageants, on which are represented, emblematical figures, artful pieces of architecture, and rural dancing : with the speeches spoken on each pageant : performed Octob. 29, 1674, for the entertainment of the Right Honourable and truly noble pattern of prudence and loyalty, Sir Robert Vyner, Kt. & Bar, Lord Mayor of the city of London : at the proper costs and charges of the worshipful Company of Goldsmiths, the Kings Most Sacred Majesty and His Royal Consort, Their Royal Highnesses the Duke and Dutchess of York, Prince Rupert, the Duke of Monmouth, several foreign embassadours, chief nobility, and secretaries of state, honouring the city with their presence /composed by Tho. JordanLondon Printed by W. Godbid for John Playford1674[4], 12 pReproduction of original in Huntington Library.eebo-0113PageantsEnglandLondonPageantsJordan Thomas1612?-1685?1000952EAAEAAm/cWaOLNBOOK996394317803316The goldsmiths' jubile, or, Londons triumphs2403935UNISA04931nam 2201105z- 450 991055737110332120220111(CKB)5400000000042180(oapen)https://directory.doabooks.org/handle/20.500.12854/76965(oapen)doab76965(EXLCZ)99540000000004218020202201d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierThe Conformational Universe of Proteins and Peptides: Tales of Order and DisorderBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 online resource (230 p.)3-0365-2352-9 3-0365-2351-0 Proteins represent one of the most abundant classes of biological macromolecules and play crucial roles in a vast array of physiological and pathological processes. The knowledge of the 3D structure of a protein, as well as the possible conformational transitions occurring upon interaction with diverse ligands, are essential to fully comprehend its biological function.In addition to globular, well-folded proteins, over the past few years, intrinsically disordered proteins (IDPs) have received a lot of attention. IDPs are usually aggregation-prone and may form toxic amyloid fibers and oligomers associated with several human pathologies. Peptides are smaller in size than proteins but similarly represent key elements of cells. A few peptides are able to work as tumor markers and find applications in the diagnostic and therapeutic fields. The conformational analysis of bioactive peptides is important to design novel potential drugs acting as selective modulators of specific receptors or enzymes. Nevertheless, synthetic peptides reproducing different protein fragments have frequently been implemented as model systems in folding studies relying on structural investigations in water and/or other environments.This book contains contributions (seven original research articles and five reviews published in the journal Molecules) on the above-described topics and, in detail, it includes structural studies on globular folded proteins, IDPs and bioactive peptides. These works were conducted usingdifferent experimental methods.Conformational Universe of Proteins and PeptidesResearch & information: generalbicsscABC transporterACE2actinadvanced sampling 5antifungal activityapparent gas phase activation energiesapparent gas phase dissociation constantsATP analoguesATP hydrolysisbackbone atom coordinate variances and uncertaintiesbinding 2bioinformaticsbiopesticidescancercharged amino acidscofactor binding and releasecytoskeletondeafnessdenatured state ensembledisordered structureDnaB helicaseELDOR-detected NMRFriedman's testgas phase immune complex dissociationhearing lossHigh Hydrostatic PressureIDP 1immunoglobulin domaininsecticidal activityinterdomain cleft dynamicsintrinsically disordered proteinsion-pairing interactionITEM-TWOmass spectrometric epitope mappingMDM2 7mechanism of actionMELD×MD 4mental illnessmolecular dynamics 3molecular dynamics simulationsn/aNAD(P)H-dependent oxidoreductasenanobodynative mass spectrometryNMRp53 6peptidepeptidesprotein aggregationprotein coil libraryprotein foldingprotein structureSARS-CoV-2schizophreniaside-chain lengthsolid-state NMRsuperimpositiontransgenic cropstransmissionTRIOBPviral spike receptor-binding domainzinc-containing alcohol dehydrogenaseβ-hairpinResearch & information: generalLeone Marilisaedt1307052Leone MarilisaothBOOK9910557371103321The Conformational Universe of Proteins and Peptides: Tales of Order and Disorder3028659UNINA