03666nam 2201141z- 450 991055736370332120231214133343.0(CKB)5400000000042255(oapen)https://directory.doabooks.org/handle/20.500.12854/77121(EXLCZ)99540000000004225520202201d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierNovel Treatment Strategies for GlioblastomaBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 electronic resource (268 p.)3-0365-2599-8 3-0365-2598-X This book is a compilation of articles that brings together current knowledge from an international team of contributors who are dedicated investigators exploring novel strategies for the treatment of glioblastoma. These articles describe some of the latest concepts that will provide students, researchers and clinicians with an overview of the therapeutic approaches being developed in the field of neuro-oncology to combat this deadly disease.Medicinebicsscglioblastomagliomatemozolomideradiotherapyimmunotherapynovel therapypersonalized treatmentdrug repurposinginvasioninvadopodiaion channelsgene therapyviral vectorsbrain tumornanomedicinecancer stem celltargeted therapybrain cancercell cycledifferentiationproliferationRASSRGAP2stem cellTP53glioblastoma multiformeGBMnerve/glial antigen 2NG2CK2CX-4945migrationCRISPR/Cas9anticanceranti-angiogenesisthyrointegrin αvβ3PEGtriazole tetracP-bi-TATP-m-TATtetracone-carbon metabolismde novo purine synthesismetabolic reprogrammingmetabolic treatmentvaccineimmune checkpoint inhibitorschimeric antigen receptor (CAR) T cellsglioblastoma (GB)prolyl-oligopeptidase (POP)vascular endothelial growth factor (VEGF)transforming growth factor-β (TGF-β)angiopoietin (Ang)endothelial nitric oxide synthase (eNOS)newly diagnosed glioblastomarecurrent glioblastomanew trial designdrug-inducible gene expressionMardepodectRegorafenibdrug targetstumor antigensrenin-angiotensin systempluripotent stem cellsorganoidscancer stem cellscancer stem cell nichetumor microenvironmentMedicineStylli Stanleyedt1314841Stylli StanleyothBOOK9910557363703321Novel Treatment Strategies for Glioblastoma3032034UNINA