03703nam 2201165z- 450 991055736370332120220111(CKB)5400000000042255(oapen)https://directory.doabooks.org/handle/20.500.12854/77121(oapen)doab77121(EXLCZ)99540000000004225520202201d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierNovel Treatment Strategies for GlioblastomaBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 online resource (268 p.)3-0365-2599-8 3-0365-2598-X This book is a compilation of articles that brings together current knowledge from an international team of contributors who are dedicated investigators exploring novel strategies for the treatment of glioblastoma. These articles describe some of the latest concepts that will provide students, researchers and clinicians with an overview of the therapeutic approaches being developed in the field of neuro-oncology to combat this deadly disease.Medicinebicsscangiopoietin (Ang)anti-angiogenesisanticancerbrain cancerbrain tumorcancer stem cellcancer stem cell nichecancer stem cellscell cyclechimeric antigen receptor (CAR) T cellsCK2CRISPR/Cas9CX-4945de novo purine synthesisdifferentiationdrug repurposingdrug targetsdrug-inducible gene expressionendothelial nitric oxide synthase (eNOS)GBMgene therapyglioblastomaglioblastoma (GB)glioblastoma multiformegliomaimmune checkpoint inhibitorsimmunotherapyinvadopodiainvasionion channelsMardepodectmetabolic reprogrammingmetabolic treatmentmigrationn/ananomedicinenerve/glial antigen 2new trial designnewly diagnosed glioblastomaNG2novel therapyone-carbon metabolismorganoidsP-bi-TATP-m-TATPEGpersonalized treatmentpluripotent stem cellsproliferationprolyl-oligopeptidase (POP)radiotherapyRASrecurrent glioblastomaRegorafenibrenin-angiotensin systemSRGAP2stem celltargeted therapytemozolomidetetracthyrointegrin αvβ3TP53transforming growth factor-β (TGF-β)triazole tetractumor antigenstumor microenvironmentvaccinevascular endothelial growth factor (VEGF)viral vectorsMedicineStylli Stanleyedt1314841Stylli StanleyothBOOK9910557363703321Novel Treatment Strategies for Glioblastoma3032034UNINA