03103nam 2200829z- 450 991055735150332120231214133337.0(CKB)5400000000042375(oapen)https://directory.doabooks.org/handle/20.500.12854/76347(EXLCZ)99540000000004237520202201d2021 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierInformation Theory in Molecular Evolution: From Models to Structures and DynamicsBasel, SwitzerlandMDPI - Multidisciplinary Digital Publishing Institute20211 electronic resource (135 p.)3-0365-1213-6 3-0365-1212-8 This Special Issue collects novel contributions from scientists in the interdisciplinary field of biomolecular evolution. Works listed here use information theoretical concepts as a core but are tightly integrated with the study of molecular processes. Applications include the analysis of phylogenetic signals to elucidate biomolecular structure and function, the study and quantification of structural dynamics and allostery, as well as models of molecular interaction specificity inspired by evolutionary cues.Information Theory in Molecular EvolutionResearch & information: generalbicsscBiology, life sciencesbicsscpower lawBrownian processKolmogorov complexityentropychaosmonofractalnon-linearcumulative sumsequence analysisprotein engineeringdirect coupling analysisevolutionary coupling analysiscontact predictionphylogenetic biasphylogenyco-evolutioncoevolutionary analysisdirect-coupling analysisspecificity determining contactssequence reweightingmaximum entropy modelsprotein contact predictionsTEM-1TOHO-1PBP-ADD-transpeptidaseconformational changescatalytic mechanismevolutionepistasisallosteryelastic network modelprotein conformational dynamicsstatistical inferencemutational phenotypesinteraction specificityphosphorylationfitness landscapebacterial signalingResearch & information: generalBiology, life sciencesMorcos Faruckedt1323406Morcos FaruckothBOOK9910557351503321Information Theory in Molecular Evolution: From Models to Structures and Dynamics3035513UNINA